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==Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue==
==Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue==


'''C–N.''' Pax9 immunostaining of taste papillae during development on cross sections (C–F; K–N) and horizontal sections of the tongue (G–J).  
Pax9 immunostaining of taste papillae during development on cross sections (C–F; K–N) and horizontal sections of the tongue (G–J).  
 
* '''C–F''' Pax9 is expressed in the epithelium during CVP morphogenesis and is down-regulated in some regions of the trenches at E18.5 (arrowhead in F).  
'''C–F''' Pax9 is expressed in the epithelium during CVP morphogenesis and is down-regulated in some regions of the trenches at E18.5 (arrowhead in F).  
* '''G–J''' In addition to the epithelium, Pax9 is also expressed in the mesenchyme during FOP development, while reduced Pax9 levels were observed in the trenches at E18.5 (arrowhead in J).  
 
* '''K–N''' In the anterior part of the tongue Pax9 is expressed in the FUP epithelium and in filiform papillae (FIP). Note that the expression is very weak or absent in the taste placodes (arrowheads). Scale bars: 200 µm in B; 50 µm in other panels.
'''G–J''' In addition to the epithelium, Pax9 is also expressed in the mesenchyme during FOP development, while reduced Pax9 levels were observed in the trenches at E18.5 (arrowhead in J).  
 
'''K–N''' In the anterior part of the tongue Pax9 is expressed in the FUP epithelium and in filiform papillae (FIP). Note that the expression is very weak or absent in the taste placodes (arrowheads). Scale bars: 200 µm in B; 50 µm in other panels.





Revision as of 11:33, 12 February 2015

Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue

Pax9 immunostaining of taste papillae during development on cross sections (C–F; K–N) and horizontal sections of the tongue (G–J).

  • C–F Pax9 is expressed in the epithelium during CVP morphogenesis and is down-regulated in some regions of the trenches at E18.5 (arrowhead in F).
  • G–J In addition to the epithelium, Pax9 is also expressed in the mesenchyme during FOP development, while reduced Pax9 levels were observed in the trenches at E18.5 (arrowhead in J).
  • K–N In the anterior part of the tongue Pax9 is expressed in the FUP epithelium and in filiform papillae (FIP). Note that the expression is very weak or absent in the taste placodes (arrowheads). Scale bars: 200 µm in B; 50 µm in other panels.


Taste Links: Image - Mouse E13.5 tongue Pax9 | Image - Mouse E13.5-18.5 tongue Pax9 | Image - Mouse tongue Pax9 | taste | PAX | tongue | mouse

Reference

<pubmed>25299669</pubmed>| PLoS Genet.


Copyright

© 2014 Kist et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. doi:10.1371/journal.pgen.1004709.g001 Cropped, Resized and relabelled from original.

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current11:15, 12 February 2015Thumbnail for version as of 11:15, 12 February 20151,200 × 833 (299 KB)Z8600021 (talk | contribs)==Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue== '''A.''' Drawing showing the localization of the circumvallate papilla (CVP), foliate papillae (FOP), and fungiform papillae (FUP) in the mouse tongue. '''B.''...

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