File:Mouse cloacal septation 01.jpg

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Mouse cloacal septation

Time-line of normal cloacal partitioning in the mouse.

  • E10 - the ventral part of the cloaca (cl) extends rostrally to give rise to the embryonic urogenital sinus and the primordium of the bladder (bl).
  • E12 - Bmp7 expression appears in the dorsal genital mesenchyme (gm).
  • E14 - Bmp7 expression in the URM shifts to the ventral portion of the genital tubercle (dashed arrow).

blue - Domains of Bmp7 expression in the urorectal mesenchyme (URM), urethral plate (up), and genital ectoderm (ge).

green - Cloacal endoderm.

rectum (r) and anus (an) urethra (ur) cloacal membrane (clm).


Links: Gastrointestinal Tract Development | Genital System Development


Reference

<pubmed>22253716</pubmed>

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029372

Citation: Xu K, Wu X, Shapiro E, Huang H, Zhang L, et al. (2012) Bmp7 Functions via a Polarity Mechanism to Promote Cloacal Septation. PLoS ONE 7(1): e29372. doi:10.1371/journal.pone.0029372

Copyright

© 2012 Xu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


doi:10.1371/journal.pone.0029372.g001

Figure 1. Journal.pone.0029372.g001.jpg panel A cropped from Figure.

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current01:59, 8 June 2012Thumbnail for version as of 01:59, 8 June 2012917 × 318 (47 KB)Z8600021 (talk | contribs)==Mouse cloacal septation== Time-line of normal cloacal partitioning in the mouse. Domains of Bmp7 expression in the urorectal mesenchyme (URM), urethral plate (up), and genital ectoderm (ge) are shown in blue. Cloacal endoderm is in green. At E10, the
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