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==Restricted spatial distribution of HOXA5 protein along the antero-posterior axis and in the respiratory and digestive tracts== | ==Restricted spatial distribution of HOXA5 protein along the antero-posterior axis and in the respiratory and digestive tracts== | ||
{{HOX}}A5 immunoreactivity is detected in the pv3-pv10 region of the prevertebral column (pvc) of {{ME12.5}} wild-type mouse embryos by immunofluorescence (bracket; A). No immunoreactivity is seen in the Hoxa5−/− specimens confirming the absence of the protein in the null mutant mouse line (B). | |||
HOXA5 is also detected in the mesenchymal component of the trachea (C), lung (D), stomach (E) and intestine (F) of | HOXA5 is also detected in the mesenchymal component of the trachea (C), lung (D), stomach (E) and intestine (F) of {{ME12.5}} mouse embryo. e, epithelium; m, mesenchyme. | ||
===Reference=== | |||
{{#pmid:20485555}} | |||
== | ====Copyright==== | ||
© 2010 Coulombe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |||
Original file name: Figure 6. Journal.pone.0010600.g006.jpg | |||
{{Footer}} | |||
[[Category:Hox]] [[Category:Mouse]] [[Category:Mouse E12.5]] [[Category:Respiratory]] [[Category:Gastrointestinal Tract]] | [[Category:Hox]] [[Category:Mouse]] [[Category:Mouse E12.5]] [[Category:Respiratory]] [[Category:Gastrointestinal Tract]] | ||
Latest revision as of 13:14, 19 July 2019
Restricted spatial distribution of HOXA5 protein along the antero-posterior axis and in the respiratory and digestive tracts
HOXA5 immunoreactivity is detected in the pv3-pv10 region of the prevertebral column (pvc) of E12.5 wild-type mouse embryos by immunofluorescence (bracket; A). No immunoreactivity is seen in the Hoxa5−/− specimens confirming the absence of the protein in the null mutant mouse line (B).
HOXA5 is also detected in the mesenchymal component of the trachea (C), lung (D), stomach (E) and intestine (F) of E12.5 mouse embryo. e, epithelium; m, mesenchyme.
Reference
Coulombe Y, Lemieux M, Moreau J, Aubin J, Joksimovic M, Bérubé-Simard FA, Tabariès S, Boucherat O, Guillou F, Larochelle C, Tuggle CK & Jeannotte L. (2010). Multiple promoters and alternative splicing: Hoxa5 transcriptional complexity in the mouse embryo. PLoS ONE , 5, e10600. PMID: 20485555 DOI.
Copyright
© 2010 Coulombe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Original file name: Figure 6. Journal.pone.0010600.g006.jpg
Cite this page: Hill, M.A. (2024, April 18) Embryology Mouse HOXA5 expression E12.5.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_HOXA5_expression_E12.5.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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