File:Mouse- embryonic stem cell signaling regulation.jpg: Difference between revisions
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==Mouse- | ==Mouse - Embryonic Etem cell regulation== | ||
Core transcriptional regulatory circuitry in pluripotent mouse ESCs. | Core transcriptional regulatory circuitry in pluripotent mouse ESCs. | ||
Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency. | Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency. | ||
:'''Links:''' {{stem cells}} | {{SOX}} | |||
===Reference=== | ===Reference=== | ||
{{#pmid:20875146}} | |||
====Copyright==== | |||
© 2010 Bourillot and Savatier; licensee BioMed Central Ltd. | |||
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||
See article [http://www.biomedcentral.com/1741-7007/8/128 BMC Biol.] | |||
Original file name: Figure 1. 1741-7007-8-125-1.jpg | |||
{{Footer}} | |||
[[Category:Mouse]] [[Category:Stem Cell]] [[Category:Molecular]] | [[Category:Mouse]] [[Category:Stem Cell]] [[Category:Molecular]] |
Latest revision as of 13:28, 21 May 2018
Mouse - Embryonic Etem cell regulation
Core transcriptional regulatory circuitry in pluripotent mouse ESCs.
Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.
- Links: stem cells | SOX
Reference
Bourillot PY & Savatier P. (2010). Krüppel-like transcription factors and control of pluripotency. BMC Biol. , 8, 125. PMID: 20875146 DOI.
Copyright
© 2010 Bourillot and Savatier; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
See article BMC Biol.
Original file name: Figure 1. 1741-7007-8-125-1.jpg
Cite this page: Hill, M.A. (2024, March 29) Embryology Mouse- embryonic stem cell signaling regulation.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-_embryonic_stem_cell_signaling_regulation.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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