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==Mouse- embryonic stem cell regulation==
==Mouse - Embryonic Etem cell regulation==


Core transcriptional regulatory circuitry in pluripotent mouse ESCs.
Core transcriptional regulatory circuitry in pluripotent mouse ESCs.


Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.  
Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.  


See article [http://www.biomedcentral.com/1741-7007/8/128 BMC Biol.]
:'''Links:''' {{stem cells}} | {{SOX}}


Original file name: Figure 1. 1741-7007-8-125-1.jpg
===Reference===
{{#pmid:20875146}}


==Reference==
====Copyright====
© 2010 Bourillot and Savatier; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


<pubmed>20875146</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946285 PMC2946285] | [http://www.biomedcentral.com/1741-7007/8/125 BMC Biol.]
See article [http://www.biomedcentral.com/1741-7007/8/128 BMC Biol.]


Original file name: Figure 1. 1741-7007-8-125-1.jpg




 
{{Footer}}
© 2010 Bourillot and Savatier; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 
[[Category:Mouse]] [[Category:Stem Cell]] [[Category:Molecular]]
[[Category:Mouse]] [[Category:Stem Cell]] [[Category:Molecular]]

Latest revision as of 13:28, 21 May 2018

Mouse - Embryonic Etem cell regulation

Core transcriptional regulatory circuitry in pluripotent mouse ESCs.

Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.

Links: stem cells | SOX

Reference

Bourillot PY & Savatier P. (2010). Krüppel-like transcription factors and control of pluripotency. BMC Biol. , 8, 125. PMID: 20875146 DOI.

Copyright

© 2010 Bourillot and Savatier; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

See article BMC Biol.

Original file name: Figure 1. 1741-7007-8-125-1.jpg



Cite this page: Hill, M.A. (2024, March 28) Embryology Mouse- embryonic stem cell signaling regulation.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-_embryonic_stem_cell_signaling_regulation.jpg

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current18:50, 24 October 2010Thumbnail for version as of 18:50, 24 October 2010600 × 442 (54 KB)S8600021 (talk | contribs)==Mouse- embryonic stem cell regulation== Core transcriptional regulatory circuitry in pluripotent mouse ESCs. Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripo