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Mouse- embryonic stem cell regulation

Core transcriptional regulatory circuitry in pluripotent mouse ESCs.

Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.

See article BMC Biol.

Original file name: Figure 1. 1741-7007-8-125-1.jpg

Reference

<pubmed>20875146</pubmed>| PMC2946285 | BMC Biol.

© 2010 Bourillot and Savatier; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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	This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.		This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

	[[Category:Mouse]] [[Category:Stem ~~Cells~~]] [[Category:Molecular]]		[[Category:Mouse]] [[Category:Stem Cell]] [[Category:Molecular]]