File:Mice mutants exhibit cleft palate and umbilical hernia.jpg

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Image shows mice mutants exhibit cleft palate and umbilical hernia

Figure 2 Viaat mutants exhibit cleft palate and umbilical hernia. (A) Gross morphology of a ViaatlacZ (−/−) mutant at E18.5 with hunched posture as compared to a wild type E18.5 littermate (+/+). (B, C) Examination of E17.5 embryos showed that all of the ViaatlacZ mutants exhibited a cleft palate (C) as compared to wild type (B). (D) Viaat mutants have small subcutaneous bumps on the dorsal side of cervical region. (E, F) Compared to wild type (E) nearly all of the ViaatlacZ mice exhibited an umbilical hernia (F). (G) Gad1lacZ mutant E17.5 mice also displayed a similar hernia phenotype.

Reference

<pubmed>20333300</pubmed> This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Assessment

+ Good example of an animal model of clefting. - You have not explained what "Viaat " is in the legend.



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Cite this page: Hill, M.A. (2024, June 15) Embryology Mice mutants exhibit cleft palate and umbilical hernia.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mice_mutants_exhibit_cleft_palate_and_umbilical_hernia.jpg

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current12:37, 18 August 2011Thumbnail for version as of 12:37, 18 August 2011527 × 332 (126 KB)Z3308968 (talk | contribs)Mice_mutants_exhibit_cleft_palate_and_umbilical_hernia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841638/?tool=pubmed Oh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unres