File:Lymph node cartoon 02.jpg
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Cell Trafficking into and out of Lymph Nodes
Lymphocytes and dendritic cells (DCs) enter lymph nodes by different routes.
Lymphocytes
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Legend
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Dendritic cells
- Dendritic cells (DCs) with small numbers of lymphocytes enter lymph nodes through the afferent lymphatics.
- then accumulate in the vicinity of high endothelial venules.
- high endothelial venules are surrounded by fibroblastic reticular cells (FRCs)
Fibroblastic reticular cells
- (FRCs) form channels (FRC conduits) that project from the subcapsular sinus into the T-cell zone.
- Some chemokines produced extranodally might reach HEVs through the FRC conduit.
See also Lymph node - high endothelial venule cartoon.
- Lymph Node Cartoons: Detailed structure | Cartoon with Histology | Lymphocyte traffic | Simple structure | Simple node anatomy | Wiki node image | Internal structure | Mesenteric lymph node | Histology | Gallery | Lymph Node Development
Reference
Miyasaka M & Tanaka T. (2004). Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. Nat. Rev. Immunol. , 4, 360-70. PMID: 15122201 DOI.
Copyright
Adapted by permission from Macmillan Publishers Ltd: Nat. Rev. Immunol.: 2004, 4(5);360-70, copyright (2004)
Licensee: Mark A Hill License Number: 2857291045727 Publication: Nature Reviews Immunology
Title: Lymphocyte trafficking across high endothelial venules: dogmas and enigmas Type Of Use: post on the internet
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Cite this page: Hill, M.A. (2024, April 24) Embryology Lymph node cartoon 02.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Lymph_node_cartoon_02.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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