File:JNK1.png: Difference between revisions

Figure: "JNK is phosphorylated during mitosis of retinal progenitor cells."

"(A, B) Representative confocal photomicrographs of immunohistochemistry for phospho-JNK (red) and phospho-histone-H3 (green) in sections of retinal tissue maintained for 3 hours in vitro either in absence (A - CTR) or presence of taxol (B - TAX) showing the NBL. The sections were counterstained with DAPI (blue). Arrows indicate examples of cells double stained for phospho-JNK and phospho-histone-H3. Scale bar: 20 µm. (C) Higher magnification of mitotic cell showing the subcellular localization of phospho-JNK (red), phospho-histone-H3 (green), and DAPI (blue). Scale bar: 10 µm. (D) Numbers of phospho-JNK or phospho-histone-H3 stained cells per 100 µm of linear extent parallel to the retinal surface, along the mitotic stratum of retinal explants maintained in vitro for 3 hours, either in the absence (CTR) or presence of taxol (TAX). (E) Percentage of cells stained for phospho-JNK among all cells immunolabeled for phospho-histone-H3 in the mitotic stratum. Data are means±S.E.M. from three independent experiments. CTR - control; TAX - taxol; NBL - neuroblastic layer; *** P<0.001 versus CTR. " doi:10.1371/journal.pone.0034483.g001

Citation: <pubmed>22496813</pubmed>

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