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(Composition of the BM in early stage follicles in human ovarian tissue. (A) Histological analysis of human ovarian tissue revealed an extracellular BM (white arrows) surrounding primordial, early primary, primary and secondary follicles. (B) Collagen I...)
 
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Composition of the BM in early stage follicles in human ovarian tissue. (A) Histological analysis of human ovarian tissue revealed an extracellular BM (white arrows) surrounding primordial, early primary, primary and secondary follicles. (B) Collagen IV (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles. (C) Laminin (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles. (D) Fibronectin (green) expression in the mesenchymal compartment of the ovarian cortex. Sporadically, we observed fibronectin expression in the BM of secondary follicles (green arrow). Scalebars are 25 μm.
==Human Ovarian Follicle Basement Membrane (BM)==
in early stage follicles in human ovarian tissue.  
 
* '''A''' - Histological analysis of human ovarian tissue revealed an extracellular BM (white arrows) surrounding primordial, early primary, primary and secondary follicles.  
* '''B''' - Collagen IV (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles.  
* '''C''' - Laminin (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles.  
* '''D''' - Fibronectin (green) expression in the mesenchymal compartment of the ovarian cortex. Sporadically, we observed fibronectin expression in the BM of secondary follicles (green arrow).  
 
Scalebar 25 μm.





Revision as of 09:19, 1 May 2015

Human Ovarian Follicle Basement Membrane (BM)

in early stage follicles in human ovarian tissue.

  • A - Histological analysis of human ovarian tissue revealed an extracellular BM (white arrows) surrounding primordial, early primary, primary and secondary follicles.
  • B - Collagen IV (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles.
  • C - Laminin (green) expression in the BM (green arrows) of primordial, early primary, primary and in secondary follicles.
  • D - Fibronectin (green) expression in the mesenchymal compartment of the ovarian cortex. Sporadically, we observed fibronectin expression in the BM of secondary follicles (green arrow).

Scalebar 25 μm.


Links: Ovary Development | Oocyte Development | Fetal Development

Reference

<pubmed>25605128</pubmed>| BMC Dev Biol.

Copyright

© 2015 Heeren et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.


Figure 8. S12861-015-0054-0-8.jpg

Heeren et al. BMC Developmental Biology 2015 15:4 doi:10.1186/s12861-015-0054-0

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