File:Human neural crest cell migration-in vitro.jpg

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Primary Human Embryo Neural Crest Cell Migration (in vitro)

  • A Human neural tube (NT) from an embryo at Carnegie stage 13.
  • B After 16 h, most hNCC have migrated away from the dorsal NT.
  • C The intact NT is detached from the culture dish.
  • D An enriched hNCC population remains, phenotypically similar to murine or avian NCC.
  • E Empirical evaluation of hNCC migration (none to few, some and many) from 31 explanted neural tubes. Third-order polynomial regressions reflect the rostral-to-caudal temporal maturation gradient of the human NT and maturation of NCC. Peaks occur during Carnegie stage 11 at cephalic levels, and during late Carnegie stage 12 at rostral trunk levels (segments extending from somites 5 through the last-formed somite pair).


Links: Carnegie stage 11 | Carnegie stage 12 | Carnegie stage 13 | Neural Crest Development

Reference

<pubmed>18689800</pubmed>| Hum Mol Genet.

Copyright

© 2008 The Author(s) This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Original File: Figure 1. http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411/DDN235F1


Cite this page: Hill, M.A. (2024, April 20) Embryology Human neural crest cell migration-in vitro.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Human_neural_crest_cell_migration-in_vitro.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current13:29, 31 August 2010Thumbnail for version as of 13:29, 31 August 20101,280 × 959 (163 KB)S8600021 (talk | contribs)==Primary Human Embryo Neural Crest Cell Migration (in vitro)== (A) Human neural tube (NT) from an embryo at Carnegie stage (C)13. (B) After 16 h, most hNCC have migrated away from the dorsal NT. (C) The intact NT is detached from the culture dish.

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