File:Gall bladder histology 005.gif

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Revision as of 17:35, 24 August 2011 by S8600021 (talk | contribs)

Gall_bladder_histology_005.gif(600 × 450 pixels, file size: 683 KB, MIME type: image/gif, looped, 12 frames, 24 s)

Human Gall Bladder Histology

Animated histology image of gall bladder wall. H&E

Anatomy

  • Pear-shaped
  • distensible sac (about 50ml volume)
  • Attached to posterioinferior surface of liver
  • Embryonic - foregut, forms from primitive bile duct
  • leads to cystic duct
    • Liver -> hepatic duct
    • Gall bladder -> cystic duct
    • Common Bile duct


Macroscopic Mucosal features:

  • Mucosa (epithelium + lamina propria)
    • Mucosal folds
    • Rokintansky-Aschoff sinuses
  • Serosa/Adventitia (dense CT + visceral mesothelium)

Epithelium

  • Columnar epithelium with microvilli (absorptive epithelium)
    • Epithelium lining the biliary system does not contain mucus-producing cells (few located in neck of gall bladder)
  • Basement membrane (not basal lamina which forms part of basement membrane and only visible by EM)

Lamina Propria

  • connective tissue
  • collagen fibers and fibroblasts
  • fenestrated capillaries and venules
  • lymphocytes and plasma cells

Smooth Muscle Layer

  • random orientation of smooth muscle cells (fibers)
  • muscularis propria (or fibromuscular coat)[1]
    • not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal)
    • various terminology used for this layer in different sources

Serosa/Adventitia

  • Dense connective tissue layer covered with visceral mesothelium epithelial layer
    • Adventitia - where it is attached to the liver
    • Serosa - where it is free in the peritoneum
  • Large blood vessels (arteries, veins)
  • Obvious lymphatic vessels
  • Autonomic nerve bundles
  • Adipose tissue

Original File name: Gall-bladder-zoom-600x450label.gif

  1. <pubmed>21074688</pubmed>

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Date/TimeThumbnailDimensionsUserComment
current17:32, 24 August 2011Thumbnail for version as of 17:32, 24 August 2011600 × 450 (683 KB)S8600021 (talk | contribs)==Human Gall Bladder Histology== Gall bladder columnar epithelium. H&E Original File name: Gall-bladder-zoom-600x450label.gif Category:Human Category:Gastrointestinal Tract Category:Histology

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