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Deletion of ''Spry'' genes leads to a doubling of CVP papillae.
This image shows the location and number of CVP papillae of WT and DKO mice. It shows that the deletion of ''Spry'' genes leads to a doubling of CVP papillae.


http://www.ncbi.nlm.nih.gov/pubmed/21655085
http://www.ncbi.nlm.nih.gov/pubmed/21655085

Latest revision as of 01:59, 5 October 2012

This image shows the location and number of CVP papillae of WT and DKO mice. It shows that the deletion of Spry genes leads to a doubling of CVP papillae.

http://www.ncbi.nlm.nih.gov/pubmed/21655085

Original Figure Explanation Deletion of Spry2 leads to a duplication of the CVP in the posterior tongue. (A) Cartoon showing location of gustatory papillae in the rodent tongue. (B,C) In situ hybridization staining of Shh. Wild-type mice possess a single CVP in the posterior tongue, whereas the CVP is duplicated in Spry2−/− mice (arrowheads). (D,E) SEM images of the tongue at E14.5. Scale bar, 500 µm. (F,G) DAPI fluorescence staining shows that the two CVPs (arrowheads) persist into adulthood in Spry2−/− mice. (D'-G') Higher magnification images of boxed areas. (D',E') Scale bar, 25 µm.

Copyright Petersen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current01:56, 5 October 2012Thumbnail for version as of 01:56, 5 October 2012456 × 465 (148 KB)Z3332337 (talk | contribs)Original Figure Explanation Deletion of Spry2 leads to a duplication of the CVP in the posterior tongue. (A) Cartoon showing location of gustatory papillae in the rodent tongue. (B,C) In situ hybridization staining of Shh. Wild-type mice possess a single
01:55, 5 October 2012Thumbnail for version as of 01:55, 5 October 2012456 × 465 (148 KB)Z3332337 (talk | contribs)Original Figure Explanation Deletion of Spry2 leads to a duplication of the CVP in the posterior tongue. (A) Cartoon showing location of gustatory papillae in the rodent tongue. (B,C) In situ hybridization staining of Shh. Wild-type mice possess a single

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