File:Fgf signalling in palate development.PNG
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Whole mounts and diagram of signalling in developing palate shelf.
Fig 8. Regulation of Shh and Fgf18 expression during palate development. (A) Whole-mount in situ detection of Shh mRNAs in wildtype embryonic palatal explants treated with BSA beads (left side) and Fgf18 beads (right side). (B) The patterns of GFP expression in ShhGFP/+ embryonic palatal explants treated with BSA beads (left side) and Fgf18 beads (right side). Note that Shh expression is inhibited by Fgf18 beads. (C) A model depicting the molecular regulation of Foxf1, Foxf2, Fgf18, and Shh expression in the developing palatal shelf. Regulation of Shh expression by Fgf10/Fgfr2b, Msx1/Bmp4, and Dlx5/Fgf7 pathways is summarized from References 8, 7, and 28, respectively.
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005769
Copyright: © 2016 Xu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- ↑ <pubmed>26745863</pubmed>
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 23:43, 27 October 2016 | | 1,634 × 1,942 (2.33 MB) | Z5017002 (talk | contribs) | Whole mounts and diagram of signalling in developing palate shelf. Fig 8. Regulation of Shh and Fgf18 expression during palate development. (A) Whole-mount in situ detection of Shh mRNAs in wildtype embryonic palatal explants treated with BSA beads (... |
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