File:Fetal adrenal ectopic germ cells 01.jpg

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Human Fetal Adrenal Ectopic Germ cells (first trimester)

Histological sections of human adrenals (and adjacent kidney) in first trimester male week 8 (GA week 10) and female week 11 (GA week 13).

(A,B) Germ cells were identified by expression of POU5F1 (red) and/or DDX4 (green).

(C,D) DDX4+ (green) germ cells do not express H2AFX (red), however, many H2AFX+ cells were present in the adrenals (white arrows).

(E,F) DDX4+ (red) germ cells were not TUNEL-positive (green), however, many TUNEL+ cells were present in the adrenals (white arrows). Note the presence of autofluorescent red blood cells. Some germ cells are highlighted in dotted boxes. Magnified views of dotted boxes are shown as inserts and the insert number corresponds to its location.

Scale bars are 200 µm in A,B,E,F, 100 µm in C,D and 20 µm in all inserts.

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Reference

<pubmed>26834021</pubmed>| Biol Open.

Copyright

© 2016. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Figure 2 relabelled.


Cite this page: Hill, M.A. (2024, March 29) Embryology Fetal adrenal ectopic germ cells 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Fetal_adrenal_ectopic_germ_cells_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current10:57, 21 May 2016Thumbnail for version as of 10:57, 21 May 20161,092 × 1,280 (358 KB)Z8600021 (talk | contribs)==Germ cells in first trimester human fetal adrenals== Histological sections of human adrenals (and adjacent kidney) in first trimester male (W10) and female (W13). (A,B) Germ cells were identified by expression of POU5F1 (red) and/or DDX4 (green). (C...

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