File:Embryonic Trachea.png

Expression of Tbx4 and Tbx5 in the developing lung and trachea

Focusing on the Trachea. At E15.5, Tbx4 and Tbx5 are expressed around the condensing cartilage mesenchyme and in the intercartilage mesenchyme (Q,R). Sox9 is expressed in the condensing cartilage rings (S).

I acknowledge that this is not the original image and that it has been edited to focus on the trachea by cutting out the top half of the original image.

Reference

Metters KM, Rossier J, Paquin J, Chrétien M & Seidah NG. (1988). Selective cleavage of proenkephalin-derived peptides (less than 23,300 daltons) by plasma kallikrein. J. Biol. Chem. , 263, 12543-53. PMID: 3410851

Copyright

Copyright Arora et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

--Mark Hill (talk) 11:18, 8 November 2014 (EST) Assessment - This is a good molecular development image, but you have not taken the opportunity to explain the roles of these factors. Your pubmed link is to the wrong reference and the copyright info should be beneath the reference. PMID 22876201 I have shown the correct reference info below. The fact that it is still here means that you have not checked your work correctly, I found the correct ref by simply searching with "The expression of Tbx4 and Tbx5 in the developing lung and trachea."

Arora R, Metzger RJ & Papaioannou VE. (2012). Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system. PLoS Genet. , 8, e1002866. PMID: 22876201 DOI.

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