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EEG in Angelman syndrome mice with a maternal deletion from Ube3a to Gabrb3

Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T), parietal (P), and occipital leads (O) alternating between left (L) and right hemisphere (R) indicated as LT, RT, LP, RP, LO, and RO. The six panels in the top tracing were continued in the lower section. Single arrow indicates the onset of sudden isolated giant spike-wave discharges with no behavioral accompaniment, and double arrow marks progression to higher spike discharge frequencies.

Original file name: Figure 4 Pone.0012278.g004.jpg

Reference

<pubmed>20808828</pubmed>| PMC:2924885 | PLoS One

Copyright Jiang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current	23:31, 17 August 2011		611 × 345 (106 KB)	Z3387190 (talk \| contribs)	==EEG in Angelman syndrome mice with a maternal deletion from Ube3a to Gabrb3== Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T)

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 ==EEG in Angelman syndrome mice with a maternal deletion from Ube3a to Gabrb3==
-Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T), parietal (P), and occipital leads (O) alternating between left (L) and right hemisphere (R) indicated as LT, RT, LP, RP, LO, and RO. The six panels in the top tracing were continued in the lower section. Single arrow indicates the onset of sudden isolated giant spike-wave discharges with no behavioral accompaniment, and double arrow marks progression to higher spike discharge frequencies
+Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T), parietal (P), and occipital leads (O) alternating between left (L) and right hemisphere (R) indicated as LT, RT, LP, RP, LO, and RO. The six panels in the top tracing were continued in the lower section. Single arrow indicates the onset of sudden isolated giant spike-wave discharges with no behavioral accompaniment, and double arrow marks progression to higher spike discharge frequencies.
-Original file name: Figure4 Pone.0012278.g004.jpg
+Original file name: Figure 4 Pone.0012278.g004.jpg
 ===Reference===
-<pubmed>20808828</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924885 PMC2924885 ] | [http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0012278 PLoS One.]
+<pubmed>20808828</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924885 PMC:2924885] | [http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0012278 PLoS One]
 Copyright Jiang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.