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EEG in Angelman syndrome mice with a maternal deletion from Ube3a to Gabrb3

Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T), parietal (P), and occipital leads (O) alternating between left (L) and right hemisphere (R) indicated as LT, RT, LP, RP, LO, and RO. The six panels in the top tracing were continued in the lower section. Single arrow indicates the onset of sudden isolated giant spike-wave discharges with no behavioral accompaniment, and double arrow marks progression to higher spike discharge frequencies.


Original file name: Figure 4 Pone.0012278.g004.jpg


Reference

<pubmed>20808828</pubmed>| PMC:2924885 | PLoS One


Copyright Jiang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current00:31, 18 August 2011Thumbnail for version as of 00:31, 18 August 2011611 × 345 (106 KB)Z3387190 (talk | contribs)==EEG in Angelman syndrome mice with a maternal deletion from Ube3a to Gabrb3== Multielectrode continuous EEG tracing shows representative generalized rapid cortical spike seizure discharge in freely moving m−/p+ deletion mice. Top-bottom: temporal (T)

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