File:Differentiation of NCC.jpg

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The neural crest cells become chromaffin precursor cells under exposure to BMP-4, and their growth and postnatal health is maintained by the secretion of glucocorticoids.


This image was inspired by the following figure on the link below, however the information was altered slightly, due to recent studies showing that glucocorticoids do not initially cause neural crest cells to become chromaffin cells, but rather BMP-4 protein[1]: https://www.ncbi.nlm.nih.gov/books/NBK10065/figure/A3132/?report=objectonly [2].

  1. Unsicker K, Huber K, Schober A & Kalcheim C. (2013). Resolved and open issues in chromaffin cell development. Mech. Dev. , 130, 324-9. PMID: 23220335 DOI.
  2. Gilbert SF. Developmental Biology. 6th edition. Sunderland (MA): Sinauer Associates; 2000. The Neural Crest. Available from: https://www.ncbi.nlm.nih.gov/books/NBK10065/

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current17:31, 10 October 2018Thumbnail for version as of 17:31, 10 October 20181,168 × 545 (75 KB)Z5091101 (talk | contribs)The neural crest cells become chromaffin precursor cells under exposure to BMP-4, and their growth and postnatal health is maintained by the secretion of glucocorticoids.

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