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(Purkinje cells (P) secrete the ligand Sonic Hedgehog (green triangles) which acts on the external granule layer (bright red circles) to increase mitosis and therefore proliferation, the Bergmann glia (B) to stimulate differentiation, and has an unknown...) |
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=Cell Signalling in Cerebellum Development= | |||
==Summary== | |||
Purkinje cells (P) secrete the ligand Sonic Hedgehog (green triangles) which acts on the external granule layer (bright red circles) to increase mitosis and therefore proliferation, the Bergmann glia (B) to stimulate differentiation, and has an unknown effect on the purkinje cells. Laminin and heparan sulfate positively affect this pathway and fibronectin and vitronectin negatively affect this pathway. | Purkinje cells (P) secrete the ligand Sonic Hedgehog (green triangles) which acts on the external granule layer (bright red circles) to increase mitosis and therefore proliferation, the Bergmann glia (B) to stimulate differentiation, and has an unknown effect on the purkinje cells. Laminin and heparan sulfate positively affect this pathway and fibronectin and vitronectin negatively affect this pathway. | ||
==Reference== | |||
==Copyright== | |||
© 2012 Manto and Jissendi. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
Revision as of 12:55, 20 October 2017
Cell Signalling in Cerebellum Development
Summary
Purkinje cells (P) secrete the ligand Sonic Hedgehog (green triangles) which acts on the external granule layer (bright red circles) to increase mitosis and therefore proliferation, the Bergmann glia (B) to stimulate differentiation, and has an unknown effect on the purkinje cells. Laminin and heparan sulfate positively affect this pathway and fibronectin and vitronectin negatively affect this pathway.
Reference
Copyright
© 2012 Manto and Jissendi. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
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