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These 3 primary brain vesicles develop initially due to the neural plate being broader at the cranial (brain) end that the narrower caudal (spinal cord) end. When the plate fuses to form a tube, these 3 initial expansions (vesicles) result.
These 3 primary brain vesicles develop initially due to the neural plate being broader at the cranial (brain) end that the narrower caudal (spinal cord) end. When the plate fuses to form a tube, these 3 initial expansions (vesicles) result.


'''Three primary brain vesicles:''' [[F#forebrain|forebrain]] ( [[P#prosencephalon|prosencephalon]]) - [[M#midbrain|midbrain]] ([[M#mesencephalon|mesencephalon]]) - [[H#hindbrain|hindbrain]] ([[R#rhombencephalon|rhombencephalon]])
'''Three primary brain vesicles:''' [[F#forebrain|forebrain]] ( [[P#prosencephalon|prosencephalon]]) - [[M#midbrain|midbrain]] ([[M#mesencephalon|mesencephalon]]) - [[H#hindbrain|hindbrain]] ([[R#rhombencephalon|rhombencephalon]])


Later they will develop into the [[:File:CNS secondary vesicles.jpg|5 secondary vesicles]].
Later they will develop into the [[:File:CNS secondary vesicles.jpg|5 secondary vesicles]].

Revision as of 14:45, 17 May 2010

Central Nervous System - primary vesicles

These 3 primary brain vesicles develop initially due to the neural plate being broader at the cranial (brain) end that the narrower caudal (spinal cord) end. When the plate fuses to form a tube, these 3 initial expansions (vesicles) result.


Three primary brain vesicles: forebrain ( prosencephalon) - midbrain (mesencephalon) - hindbrain (rhombencephalon)


Later they will develop into the 5 secondary vesicles.

Links: Neural System Development


Image: The development of the three primary brain vesicles on GD 10.5 in rats and GD 26 ± 1 in humans. The corresponding shading between panels illustrates the earlier origins of different regions from the three original brain vesicles with a horizontal and lateral view, respectively.

Original file name: Figure-3AB-PMID10852851.jpg

Image Source: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Rice D, Barone S Jr. Environ Health Perspect. 2000 Jun;108 Suppl 3:511-33. Review. PMID: 10852851 | Environmental Health Perspectives - Critical Periods of Vulnerability for the Developing Nervous System: Evidence from Humans and Animal Models | PMC: 1637807 |

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current16:48, 18 May 2017Thumbnail for version as of 16:48, 18 May 2017987 × 562 (49 KB)Z8600021 (talk | contribs)
16:18, 5 April 2017Thumbnail for version as of 16:18, 5 April 2017961 × 462 (45 KB)Z8600021 (talk | contribs)
01:01, 11 August 2009Thumbnail for version as of 01:01, 11 August 2009961 × 462 (50 KB)MarkHill (talk | contribs)CNS primary vesicles cartoon Figure-3AB-PMID10852851.jpg Image Source: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Rice D, Barone S Jr. Environ Health Perspect. 2000 Jun;108 Suppl 3:511-33