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==Bradley M. Patten==
==Bradley M. Patten==
Bradley Merrill Patten ( -1971) was an American embryologist, Western Reserve University, School of Medicine. Cleveland, Ohio.


Author of textbook [[Book_-_The_Early_Embryology_of_the_Chick|The Early Embryology of the Chick]] Philadelphia: P. Blakiston's Son and Co. (1920)
Bradley Merrill Patten, the distinguished embryologist, is retiring from active service as Professor of Anatomy and Chairman of the Department of Anatomy in the Medical School, University of Michigan.


The son of a professor of zoology at Dartmouth College, he entered upon his own academic career with characteristic single-mindedness graduating from Dartmouth Phi Beta Kappa in 1911, and from Harvard Graduate School in 1914.


See also: [http://onlinelibrary.wiley.com/doi/10.1002/aja.1000480104/abstract The closure of the foramen oval (1931)] | [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1709696/pdf/canmedaj00477-0194b.pdf JAMA Review of - Embryology of the Pig] | [http://openlibrary.org/authors/OL548090A/Bradley_M._Patten?sort=new Open Library]


:'''Links:''' {{Patten BM.}}


Bradley M. Patten. Western Reserve University, School of Medicine. Cleveland, Ohio.


===References===
{{Ref-Patten1920}}
{{Ref-Patten1938}}
Human Embryology. Ed. 2. Bradley M. Patten, Ph.D. New York, The Blakiston Company, 1953.
{{Ref-Patten1951}}
[http://onlinelibrary.wiley.com/doi/10.1002/aja.1000480104/abstract The closure of the foramen oval (1931)] | [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1709696/pdf/canmedaj00477-0194b.pdf JAMA Review of - Embryology of the Pig] | [http://openlibrary.org/authors/OL548090A/Bradley_M._Patten?sort=new Open Library]
In memoriam: Bradley M. Patten. Dev. Biol.: 1971, 26(4);659 PMID 4944077
BRADLEY M. PATTEN. Med Bull (Ann Arbor): 1958, 24(12);500-1 PMID 13625453
{{External Links}}
See also:
* University of Michigan Faculty History [http://um2017.org/faculty-history/faculty/bradley-merrill-patten/memoir Bradley M. Patten]
===Embryological stages in the development of spina bifida and myelosclzisis===
This 1946 paper presented by Patten at the 1946 Meeting of the American Association of Anatomists.
Bradley M. PATTEN, Department of Anatomy, University of Michigan.
Three recently acquired human embryos show progressive stages in the development of spina bifida and myeloschisis. The youngest (8 mm) exhibits a broad
opening of the neural tube in the sacral region. Measurements of the sections
show the bulk of the spinal cord is startlingly greater ill the region of the defect
than just above or below it. Similarly in the second embryo (49 mm) there is
marked overgrowth of the cord with the additional factor of local cord duplication
toward one end of the defect. The third specimen (160 mm) is beginning to show
degenerative changes in the open cord and clubbing of the feet. The youngest
embryo indicates the cord defect is primary because it has been established well
before the primordia of the neural arches have begun to take shape. Conditions
presented by these specimens strongly suggest that the open neural tube is the
result of local overgrowth which interfered with closure, rather than the result
of a “developmental arrest” which left the tube unclosed. The importance of this
possibility lies in its implications as to causation. Because of the emphasis which
has been placed on the developmental arrest concept, search for causes of congenital defects has been largely directed toward conditions which might inhibit
growth. If anomalies are caused also by local overgrowth, we must scrutinize
causative factors of different types.
{{Footer}}
[[Category:People]]
[[Category:Historic Embryology]]
[[Category:Historic Embryology]]
[[Category:USA]]

Latest revision as of 22:44, 15 April 2019

Bradley M. Patten

Bradley Merrill Patten ( -1971) was an American embryologist, Western Reserve University, School of Medicine. Cleveland, Ohio.

Bradley Merrill Patten, the distinguished embryologist, is retiring from active service as Professor of Anatomy and Chairman of the Department of Anatomy in the Medical School, University of Michigan.

The son of a professor of zoology at Dartmouth College, he entered upon his own academic career with characteristic single-mindedness graduating from Dartmouth Phi Beta Kappa in 1911, and from Harvard Graduate School in 1914.


Links: Patten BM.


References

Patten BM. The Early Embryology of the Chick. (1920) Philadelphia: P. Blakiston's Son and Co.

Patten BM. Developmental defects at the foramen ovale. (1938) Am J Pathol. 14(2):135-162. PMID 19970381

Human Embryology. Ed. 2. Bradley M. Patten, Ph.D. New York, The Blakiston Company, 1953.

Patten BM. Embryology of the Pig. (1951) The Blakiston Company, Toronto.

The closure of the foramen oval (1931) | JAMA Review of - Embryology of the Pig | Open Library

In memoriam: Bradley M. Patten. Dev. Biol.: 1971, 26(4);659 PMID 4944077

BRADLEY M. PATTEN. Med Bull (Ann Arbor): 1958, 24(12);500-1 PMID 13625453


External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation. See also:

Embryological stages in the development of spina bifida and myelosclzisis

This 1946 paper presented by Patten at the 1946 Meeting of the American Association of Anatomists.

Bradley M. PATTEN, Department of Anatomy, University of Michigan.

Three recently acquired human embryos show progressive stages in the development of spina bifida and myeloschisis. The youngest (8 mm) exhibits a broad opening of the neural tube in the sacral region. Measurements of the sections show the bulk of the spinal cord is startlingly greater ill the region of the defect than just above or below it. Similarly in the second embryo (49 mm) there is marked overgrowth of the cord with the additional factor of local cord duplication toward one end of the defect. The third specimen (160 mm) is beginning to show degenerative changes in the open cord and clubbing of the feet. The youngest embryo indicates the cord defect is primary because it has been established well before the primordia of the neural arches have begun to take shape. Conditions presented by these specimens strongly suggest that the open neural tube is the result of local overgrowth which interfered with closure, rather than the result of a “developmental arrest” which left the tube unclosed. The importance of this possibility lies in its implications as to causation. Because of the emphasis which has been placed on the developmental arrest concept, search for causes of congenital defects has been largely directed toward conditions which might inhibit growth. If anomalies are caused also by local overgrowth, we must scrutinize causative factors of different types.



Cite this page: Hill, M.A. (2024, March 29) Embryology Bradley M. Patten.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Bradley_M._Patten.jpg

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current11:42, 29 July 2011Thumbnail for version as of 11:42, 29 July 2011600 × 508 (34 KB)S8600021 (talk | contribs)==Bradley M. Patten== Author of textbook The Early Embryology of the Chick Philadelphia: P. Blakiston's Son and Co. (1920) Bradley M. Patten. Western Reserve University, School of Medicine. Cleveland, Ohio.