File:Bone marrow histology 02.jpg: Difference between revisions

Bone Marrow Histology

See matching field image showing adipocytes and blood sinusoids.

Megakaryoblast

• precursor of megakaryocyte.
• earliest identifiable precursor in the thrombocytic series.
• matures to form the promegakaryocyte.

Megakaryocyte

• largest cells observed in the bone marrow.
• responsible for platelet production.
• develop through a process called endoreduplication, which forms cells with 16N and 32N chromosomal content.
• large amount of DNA increases protein production and cytoplasm volume.
• platelets begin to form by pinching off from the cell surface.

Thrombocyte

• platelets form by pinching off from the cell surface of a megakaryocytic.
  • not easily seen in bone marrow, visible in blood.
• cell fragment ( 2-3 microns in diameter) with 5-9 day lifespan.
• normal range in blood 150,000-450,000/mm³ (ml)
• abnormal levels in bone marrow or blood disorders.

Bone Marrow Histology: Blood Development | Marrow overview | Megakaryocyte | Megakaryocyte detail | Myelocyte | Normoblast | Reticulocyte | Blood Histology | Bone Development | Category:Blood

Links: Histology | Histology Stains | Blue Histology images copyright Lutz Slomianka 1998-2009. The literary and artistic works on the original Blue Histology website may be reproduced, adapted, published and distributed for non-commercial purposes. See also the page Histology Stains.

Cite this page: Hill, M.A. (2024, April 19) Embryology Bone marrow histology 02.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Bone_marrow_histology_02.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G