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Heparin induces polyspermy and abnormal formation of fertilization cones
Formation of the fertilization cone was monitored in living eggs after sperm addition. (A) F-actin was visualized by microinjection of fluorescent phalloidin. (B) Transmission photomicrographs of the same eggs. Both phalloidin-stained actin networks and the transmission photomicrographs displayed formation of single and round fertilization cone (arrow) in the control egg by 9 min after adding sperm. In contrast, heparin-treated eggs displayed abnormal formation of multiple and piriform-shaped fertilization cones (arrowheads).
(Original figure legend, image based on data PMID 18974786)
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|current||15:33, 14 August 2015||256 × 256 (5 KB)||Z5015752||Original file name: tileshop.fcgi.jpg PMID: 18974786|