Europe Statistics

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Introduction

Europe
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Some Recent Findings

  • Paper 2: EUROCAT public health indicators for congenital anomalies in Europe.[1] "The purpose of this article is to present the specific public health indicators recently developed by EUROCAT that aim to summarize important aspects of the public health impact of congenital anomalies in a few quantitative measures. The six indicators are: (1) congenital anomaly perinatal mortality, (2) congenital anomaly prenatal diagnosis prevalence, (3) congenital anomaly termination of pregnancy, (4) Down syndrome livebirth prevalence, (5) congenital anomaly pediatric surgery, and (6) neural tube defects (NTD) total prevalence. Data presented for this report pertained to all cases (livebirths, fetal deaths, or stillbirths after 20 weeks of gestation and terminations of pregnancy for fetal anomaly [TOPFA]) of congenital anomaly from 27 full member registries of EUROCAT that could provide data for at least 3 years during the period 2004 to 2008. Prevalence of anomalies, prenatal diagnosis, TOPFA, pediatric surgery, and perinatal mortality were calculated per 1000 births."
  • The prevalence of congenital anomalies in Europe.[2]EUROCAT (European Surveillance of Congenital Anomalies) is the network of population-based registers of congenital anomaly in Europe, with a common protocol and data quality review, covering 1.5 million annual births in 22 countries. EUROCAT recorded a total prevalence of major congenital anomalies of 23.9 per 1,000 births for 2003-2007. 80% were livebirths. 2.5% of livebirths with congenital anomaly died in the first week of life. 2.0% were stillbirths or fetal deaths from 20 weeks gestation. 17.6% of all cases were terminations of pregnancy following prenatal diagnosis (TOPFA). Thus, congenital anomalies overwhelmingly concern children surviving the early neonatal period, who have important medical, social or educational needs. The prevalence of chromosomal anomalies was 3.6 per 1,000 births, contributing 28% of stillbirths/fetal deaths from 20 weeks gestation with congenital anomaly, and 48% of all TOPFA. Congenital heart defects (CHD) were the most common non-chromosomal subgroup, at 6.5 per 1,000 births, followed by limb defects (3.8 per 1,000), anomalies of urinary system (3.1 per 1,000) and nervous system defects (2.3 per 1,000). In 2004, perinatal mortality associated with congenital anomaly was 0.93 per 1,000 births, and TOPFA 4.4 per 1,000 births, with considerable country variation. Primary prevention of congenital anomalies in the population based on controlling environmental risk factors is a crucial policy priority, including preconceptional care and whole population approaches."

Statistical Data

The following data is from a 2010 EUROCAT paper.[2]

  • total prevalence of major congenital anomalies of 23.9 per 1,000 births for 2003-2007.
    • 80% were livebirths.
    • 2.5% of livebirths with congenital anomaly died in the first week of life.
    • 2.0% were stillbirths or fetal deaths from 20 weeks gestation.
  • 17.6% of all cases were terminations of pregnancy following prenatal diagnosis (TOPFA).
  • prevalence of chromosomal anomalies was 3.6 per 1,000 births.
    • contributing 28% of stillbirths/fetal deaths from 20 weeks gestation with congenital anomaly
    • 48% of all TOPFA.
  • Congenital heart defects (CHD) were the most common non-chromosomal subgroup (6.5 per 1,000 births).
  • Limb defects (3.8 per 1,000)
  • Renal anomalies (3.1 per 1,000)
  • Neural defects (2.3 per 1,000).

2004 - perinatal mortality associated with congenital anomaly was 0.93 per 1,000 births, and TOPFA 4.4 per 1,000 births, with considerable country variation.

Italy

Brindisi, Italy

Congenital anomalies among live births in a polluted area[3] "Congenital anomalies and their primary prevention are a crucial public health issue. This work aimed to estimate the prevalence of congenital anomalies in Brindisi, a city in southeastern Italy at high risk of environmental crisis. This research concerned newborns up to 28 days of age, born between 2001 and 2010 to mothers resident in Brindisi and discharged with a diagnosis of congenital anomaly. ...Our findings indicated an increased prevalence of Congenital Anomalies (especially congenital heart diseases) in the city of Brindisi. More research is needed in order to analyze the role of factors potentially involved in the causation of congenital anomalies."


References

  1. <pubmed>21381186</pubmed>
  2. 2.0 2.1 <pubmed>20824455</pubmed>
  3. <pubmed>23270371</pubmed>


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  • EUROCAT (European Surveillance of Congenital Anomalies) funding from the European Union, in the framework of the Public Health Programme, a WHO Collaborating Centre for the Surveillance of Congenital Anomalies and based at the University of Ulster. EUROCAT


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Cite this page: Hill, M.A. (2024, March 28) Embryology Europe Statistics. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Europe_Statistics

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