Endocrine - Thymus Development: Difference between revisions
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[[File:Pharyngeal_pouches.jpg|thumb|Embryonic origins of the endocrine organs of the neck]] | [[File:Pharyngeal_pouches.jpg|thumb|Embryonic origins of the endocrine organs of the neck]] | ||
The thymus has two origins for the lymphoid thymocytes and the thymic epithelial cells. The thymic epithelium begins as two flask-shape endodermal diverticula that form from the third pharyngeal pouch and extend lateralward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta. | The thymus has two origins for the lymphoid thymocytes and the thymic epithelial cells. The thymic epithelium begins as two flask-shape endodermal diverticula that form from the third pharyngeal pouch and extend lateralward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta. The immune system T cells are essential for responses against infections and much research concerns the postnatal development of T cells within the thymus. | ||
:{{Template:Endocrine Links}} | [[2009_Lecture_11|Lecture - Head Development]] | [http://embryology.med.unsw.edu.au/Notes/endocrine13.htm original page] | :{{Template:Endocrine Links}} | [[2009_Lecture_11|Lecture - Head Development]] | [http://embryology.med.unsw.edu.au/Notes/endocrine13.htm original page] | ||
==Some Recent Findings== | ==Some Recent Findings== |
Revision as of 14:30, 23 July 2010
Introduction
The thymus has two origins for the lymphoid thymocytes and the thymic epithelial cells. The thymic epithelium begins as two flask-shape endodermal diverticula that form from the third pharyngeal pouch and extend lateralward and backward into the surrounding mesoderm and neural crest-derived mesenchyme in front of the ventral aorta. The immune system T cells are essential for responses against infections and much research concerns the postnatal development of T cells within the thymus.
| Lecture - Head Development | original page
Some Recent Findings
Thymus Development
- Endoderm - third pharyngeal pouch
- Week 6 - diverticulum elongates, hollow then solid, ventral cell proliferation
- Thymic primordia - surrounded by neural crest mesenchyme, epithelia/mesenchyme interaction
- Thymus - bone-marrow lymphocyte precursors become thymocytes, and subsequently mature into T lymphocytes (T cells)
- Thymus hormones - thymosins stimulate the development and differentiation of T lymphocytes
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Cite this page: Hill, M.A. (2024, April 19) Embryology Endocrine - Thymus Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Endocrine_-_Thymus_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G