Endocrine - Gonad Development

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Introduction

Female HPG axis

Lecture - Genital Development | UNSW Embryology - Gonads see also previous Sexual Differentiation Lecture/Practical

HPG Axis - Endocrinology - Simplified diagram of the actions of gonadotrophins

Gonad Development

  • mesoderm - mesothelium and underlying mesenchyme, primordial germ cells
  • Gonadal ridge - mesothelium thickening, medial mesonephros
  • Primordial Germ cells - yolk sac, to mesentery of hindgut, to genital ridge of developing kidney

Differentiation

  • testis-determining factor (TDF) from Y chromosome: presence (testes), absence (ovaries)

Testis

  • 8 Weeks, mesenchyme, interstitial cells (of Leydig) secrete testosterone, androstenedione
  • 8 to 12 Weeks - hCG stimulates testosterone production
  • Sustentacular cells - produce anti-mullerian hormone to puberty

Ovary

  • X chromosome genes regulate ovary development

References


Reviews

Articles

Search PubMed

Search April 2010

  • Endocrine Development - All (14277) Review (4620) Free Full Text (3140)

Search Pubmed: pineal development

Additional Images

Adult Histology

Terms

Glossary Links

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Cite this page: Hill, M.A. (2019, July 19) Embryology Endocrine - Gonad Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Endocrine_-_Gonad_Development

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G