Endocrine - Gonad Development

From Embryology
Revision as of 13:03, 25 April 2010 by S8600021 (talk | contribs) (Created page with '==Gonad== thumb|Female HPG axis Lecture - Genital Development | [http://embryology.med.unsw.edu.au/Notes/endocrine15.htm UNSW Embryolog…')
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)


Female HPG axis

Lecture - Genital Development | UNSW Embryology - Gonads see also previous Sexual Differentiation Lecture/Practical

HPG Axis - Endocrinology - Simplified diagram of the actions of gonadotrophins

Gonad Development

  • mesoderm - mesothelium and underlying mesenchyme, primordial germ cells
  • Gonadal ridge - mesothelium thickening, medial mesonephros
  • Primordial Germ cells - yolk sac, to mesentery of hindgut, to genital ridge of developing kidney


  • testis-determining factor (TDF) from Y chromosome: presence (testes), absence (ovaries)


  • 8 Weeks, mesenchyme, interstitial cells (of Leydig) secrete testosterone, androstenedione
  • 8 to 12 Weeks - hCG stimulates testosterone production
  • Sustentacular cells - produce anti-mullerian hormone to puberty


  • X chromosome genes regulate ovary development