Endocrine - Gonad Development

Introduction

Female HPG axis

Lecture - Genital Development | UNSW Embryology - Gonads see also previous Sexual Differentiation Lecture/Practical

HPG Axis - Endocrinology - Simplified diagram of the actions of gonadotrophins

Gonad Development

• mesoderm - mesothelium and underlying mesenchyme, primordial germ cells
• Gonadal ridge - mesothelium thickening, medial mesonephros
• Primordial Germ cells - yolk sac, to mesentery of hindgut, to genital ridge of developing kidney

Differentiation

• testis-determining factor (TDF) from Y chromosome: presence (testes), absence (ovaries)

Testis

• 8 Weeks, mesenchyme, interstitial cells (of Leydig) secrete testosterone, androstenedione
• 8 to 12 Weeks - hCG stimulates testosterone production
• Sustentacular cells - produce anti-mullerian hormone to puberty

Ovary

• X chromosome genes regulate ovary development

References

Search PubMed

Search April 2010

• Endocrine Development - All (14277) Review (4620) Free Full Text (3140)

Search Pubmed: pineal development

Additional Images

Adult Histology

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  Pineal (high power)

Glossary Links

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Cite this page: Hill, M.A. (2024, April 23) Embryology Endocrine - Gonad Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Endocrine_-_Gonad_Development

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G