Difference between revisions of "Embryology History - Santiago Ramón y Cajal"

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Revision as of 17:03, 30 October 2017

Introduction

Santiago Ramon y Cahal (photograph)
Historic retina drawing

Santiago Ramon y Cahal (1852 - 1934) and Camillo Golgi (1843 - 1926) jointly received the Nobel Prize in Medicine in 1906 "in recognition of their work on the structure of the nervous system."

A Spanish researcher who used then new histology Golgi staining techniques to identify the cerebellum cellular structure. His work was a turning point in our understanding of the structure of the brain, that until then had been described as a "syncytium" and not consisting of discrete cellular elements. For this research and other work on defining the structure of the brain he, along with Camillo Golgi (1843 - 1926), received the 1906 Nobel Prize in Medicine.

Links: 1899 Human Sensory Cortex 1904 - A Brief History of Science | Retina | History - Early 20th Century | Category:Cajal


From the 1990 Science book review.[1]

"The neuroanatomist Santiago Ramon y Cahal might be considered something of a pioneer in the autobiographical genre, his straightforwardly titled Recuerdos de Mi Vida having appeared, in two volumes, in 1901 and 1907. The work was translated into English in 1937 and published as volume 8 of the Memoirs of the American Philosophical Society, itself now a long-standing sponsor of such works."

Santiago Ramon y Cahal in laboratory.jpg

Santiago Ramon y Cahal in laboratory portrait.

Camillo Golgi
Camillo Golgi.jpg
Camillo Golgi (1843 - 1926) developed the histology silver staining technique, the basis of Cajal's study of the brain.

Golgi today though is best known for the cellular organelle that bears his name, the Golgi apparatus.


Embryologists: William Hunter | Wilhelm Roux | Caspar Wolff | Wilhelm His | Oscar Hertwig | Julius Kollmann | Hans Spemann | Francis Balfour | Charles Minot | Ambrosius Hubrecht | Charles Bardeen | Franz Keibel | Franklin Mall | Florence Sabin | George Streeter | George Corner | James Hill | Jan Florian | Thomas Bryce | Thomas Morgan | Ernest Frazer | Francisco Orts-Llorca | José Doménech Mateu | Frederic Lewis | Arthur Meyer | Robert Meyer | Erich Blechschmidt | Klaus Hinrichsen | Hideo Nishimura | Arthur Hertig | John Rock | Viktor Hamburger | Mary Lyon | Nicole Le Douarin | Robert Winston | Fabiola Müller | Ronan O'Rahilly | Robert Edwards | John Gurdon | Shinya Yamanaka | Embryology History | Category:People
Related Histology Researchers  
Santiago Ramón y Cajal | Camillo Golgi

Historic Drawings

Neural- cortex Cajal drawing 01.jpg
adult human visual cortex adult human motor cortex infant human (1.5 month)
Nissl-stain Nissl-stain Golgi-stain



Cajal bodies

Nucleus Cajal bodies image
Cajal bodies[2]

(CB) Ramon y Cajal originally identified these small (20-25 nm) nuclear membraneless organelles in cells, they have various suggested functions and are localized to the nucleolar periphery or within the nucleoli. They contain both newly assembled small nuclear ribonucleoproteins (snRNPs, for pre-mRNA splicing) and small nucleolar ribonucleoproteins (snoRNPs, for ribosomal RNA processing) particles.


See also the review.[3]


References

  1. <pubmed>17735292</pubmed>| Book Review
  2. <pubmed>12379800</pubmed>| PMC2173504 | J Cell Biol.
  3. <pubmed>14685175</pubmed>


<pubmed>14944970</pubmed>

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Cite this page: Hill, M.A. (2019, October 18) Embryology Embryology History - Santiago Ramón y Cajal. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Embryology_History_-_Santiago_Ram%C3%B3n_y_Cajal

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G