Embryology History - Arthur Hertig

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Arthur T Hertig
Arthur Tremain Hertig (1904-1990)

Introduction

Prof Arthur Tremain Hertig (1904-1990) was professor of pathology at Harvard Medical School and chairman of the school's Department of Pathology (1952 to 1968). A pathologist and researcher on human embryology. He also contributed to the development by others of the contraceptive pill and in vitro fertilization.


His early papers were often co-authored with John Rock and included embryos that were incorporated into the Carnegie Collection.


Stage5 bf8004.jpg

Carnegie Collection Embryo No. 8004 (stage 5b) from 1945 paper.[1]


John Charles Rock
John Charles Rock (1890-1984)

John Rock

John Charles Rock (1890-1984) was a Boston gynaecologist and human fertility researcher. In 1938 he began a collaboration with Arthur Hertig and the researcher Miriam Menkin (1901 – 1992; née Miriam Friedman).


Both Rock and Menkin looked within the surgically removed uterine tubes and uterus for the earliest stages of human development the "products of conception".


They were also the earliest researchers looking at human in vitro fertilisation techniques[2] for treatment of infertility, what is today called Assisted Reproductive Technology or (ART).


John Rock was also the main subject of a recent book on changes in reproduction.[3]


Links: Assisted Reproductive Technology

References

  1. Hertig AT. and Rock J. Two human ova of the pre-villous stage, having a developmental age of about seven and nine days respectively. (1945) Contrib. Embryol., Carnegie Inst. Wash. Publ. 557, 31: 65-84.
  2. Rock J. and Menkin MF. In vitro fertilization and cleavage of human ovarian eggs. (1944) Science 100 (2588): 105-107. PMID 17788930
  3. Marsh M. and Ronner W. The Fertility Doctor: John Rock and the Reproductive Revolution. (2008) Baltimore: Johns Hopkins University Press. Pp. x, 374. ISBN 978-0-801-89001-7.


Hertig AT. Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey. (1935) Carnegie Instn. Wash. Publ. 459, Contrib. Embryol. 25: 37-81.

Hertig AT. and Rock J. Two human ova of the pre-villous stage, having an ovulation age of about eleven and twelve days respectively. (1941) Carnegie Instn. Wash. Publ. 525, Contrib. Embryol., 29: 127-156.

Hertig AT. and Rock J. On the development of the early human ovum, with special reference to the trophoblast of the previllous stage: A description of a normal and 5 pathologic human ova. (1944) Amer. J. Obstet Gynecol., 47: 149-184.

Hertig AT. and Rock J. Two human ova of the pre-villous stage, having a developmental age of about seven and nine days respectively. (1945) Contrib. Embryol., Carnegie Inst. Wash. Publ. 557, 31: 65-84.

Hertig AT. and Rock J. On a normal human ovum not over 7.5 days of age. (1945) Anat. Rec. 91: 281.

Hertig AT. and Rock J. On a normal ovum of approximately 9 to 10 days of age. (1945) Anat. Rec. 91: 281.

Hertig AT. and Rock J. On a human blastula recovered from the uterine cavity 4 days after ovulation. (1946) J Gerontol. 1(1): 96-117.

Hertig AT. and Rock J. Two human ova of the pre-villous stage, having a developmental age of about eight and nine days respectively. (1949) Contrib. Embryol., Carnegie Inst. Wash. Publ. 583, 33: 169-186.

Hertig AT. Rock J. and Adams EC. A description of 34 human ova within the first 17 days of development. (1956) Amer. J Anat., 98:435-493.

Hertig AT. Rock J. Adams EC. and Mulligan W.J. On the preimplantation stages of the human ovum: a description of four normal and four abnormal specimens ranging from the second to the fifth day of development. (1954) Carnegie Instn. Wash. Publ. 603, Contrib. Embryol., 35: 199-220.

Hertig AT. Rock J. and Adams EC. A description of 34 human ova within the first 17 days of development. (1956) Amer. J Anat., 98:435-493.

Hertig AT. Adams EC. Mckay DG. Rock J. Mulligan WJ. and Menkin MF. A thirteen-day human ovum studied histochemically. (1958) Am. J. Obstet. Gynecol., 76(5): 1025-40. PMID 13583048

Template:Ref-Hertig1968

Hertig AT. and Rock J. Searching for early fertilized human ova. (1973) Gynecol. Invest., 4: 121-139.


Search PubMed: Hertig AT



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John Rock


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Cite this page: Hill, M.A. (2024, March 28) Embryology Embryology History - Arthur Hertig. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Embryology_History_-_Arthur_Hertig

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