Dolphin Development: Difference between revisions

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==Limb Development==
==Limb Development==
[[Dolphin_limb_development_01.jpg|thumb|Hind-limb loss in embryos of the dolphin.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref>]]
[[File:Dolphin_limb_development_01.jpg|thumb|Hind-limb loss in embryos of the dolphin.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref>]]
Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref> The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week.
Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud. An absence of Hand2, an upstream regulator of Shh, leads to the failure to establish a ZPA.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref> The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week.


[[File:Dolphin limb development 02.jpg|600px]]
[[File:Dolphin limb development 02.jpg|600px]]
:'''Links:''' [[Musculoskeletal_System_-_Limb_Development|Limb Development]] | [[Developmental_Signals_-_Sonic_hedgehog|Sonic hedgehog]]


== References ==
== References ==

Revision as of 01:56, 22 February 2011

Introduction

Some Recent Findings

  • Hibernation and reproduction overlap in the echidna. [1] "During hibernation there is a slowing of all metabolic

Taxon

Development Overview

Limb Development

Hind-limb loss in embryos of the dolphin.[2]

Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud. An absence of Hand2, an upstream regulator of Shh, leads to the failure to establish a ZPA.[2] The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week.

Dolphin limb development 02.jpg

Links: Limb Development | Sonic hedgehog

References

  1. <pubmed>19562080</pubmed>
  2. 2.0 2.1 <pubmed>16717186</pubmed>| PNAS

Reviews

<pubmed></pubmed>


Articles

<pubmed></pubmed>


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Cite this page: Hill, M.A. (2024, April 20) Embryology Dolphin Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Dolphin_Development

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