Dolphin Development: Difference between revisions
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==Limb Development== | ==Limb Development== | ||
[[Dolphin_limb_development_01.jpg|thumb|Hind-limb loss in embryos of the dolphin.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref>]] | [[File:Dolphin_limb_development_01.jpg|thumb|Hind-limb loss in embryos of the dolphin.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref>]] | ||
Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref> The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week. | Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud. An absence of Hand2, an upstream regulator of Shh, leads to the failure to establish a ZPA.<ref name="PMID16717186"><pubmed>16717186</pubmed>| [http://www.pnas.org/content/103/22/8414.long PNAS]</ref> The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week. | ||
[[File:Dolphin limb development 02.jpg|600px]] | [[File:Dolphin limb development 02.jpg|600px]] | ||
:'''Links:''' [[Musculoskeletal_System_-_Limb_Development|Limb Development]] | [[Developmental_Signals_-_Sonic_hedgehog|Sonic hedgehog]] | |||
== References == | == References == |
Revision as of 01:56, 22 February 2011
Introduction
Some Recent Findings
- Hibernation and reproduction overlap in the echidna. [1] "During hibernation there is a slowing of all metabolic
Taxon
Development Overview
Limb Development
Researchers have identified that Sonic hedgehog (Shh), that in limb development is the signaling activity of the zone of polarizing activity (ZPA), is absent from the dolphin hind-limb bud. An absence of Hand2, an upstream regulator of Shh, leads to the failure to establish a ZPA.[2] The hind-limb bud initiates, but then bud arrests and degenerates around the fifth gestational week.
- Links: Limb Development | Sonic hedgehog
References
Reviews
<pubmed></pubmed>
Articles
<pubmed></pubmed>
Books
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Cite this page: Hill, M.A. (2024, April 20) Embryology Dolphin Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Dolphin_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G