Developmental Signals - Pax: Difference between revisions
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* '''Downstream genes of Pax6 in the developing rat hindbrain''' <ref><pubmed>20082710</pubmed>| [http://www.biomedcentral.com/1471-213X/10/6 BMC Dev. Biol.] "These results indicate that Unc5h1 and Cyp26b1 are novel candidates for target genes transactivated by Pax6. Furthermore, our results suggest the interesting possibility that Pax6 regulates anterior-posterior patterning of the hindbrain via activation of Cyp26b1, an enzyme that metabolizes retinoic acid." | * '''Downstream genes of Pax6 in the developing rat hindbrain''' <ref><pubmed>20082710</pubmed>| [http://www.biomedcentral.com/1471-213X/10/6 BMC Dev. Biol.] "These results indicate that Unc5h1 and Cyp26b1 are novel candidates for target genes transactivated by Pax6. Furthermore, our results suggest the interesting possibility that Pax6 regulates anterior-posterior patterning of the hindbrain via activation of Cyp26b1, an enzyme that metabolizes retinoic acid." | ||
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==References== | |||
<references/> | |||
'''Search Bookshelf''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Books&cmd=search&term=Pax Pax] | |||
===Search Pubmed=== | |||
'''Search Pubmed Now:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Pax Pax] | |||
==External Links== | |||
* OMIM - [http://www.ncbi.nlm.nih.gov/pubmed/19736321 PMID: 19736321] | |||
{{Template:Glossary}} | |||
{{Template:Footer}} | |||
[[Category:Pax]] [[Category:Molecular]] [[Category:Pattern]] | |||
[[Category:Neural]] | |||
Revision as of 17:09, 22 September 2010
Introduction
The name derived from Drosophila gene "paired" (prd) with a box (homeodomain) domain. A transcription factor of the helix-turn-helix structural family, DNA binding, and activating gene expression. In human, there are nine member proteins from Pax1 to Pax9.
Pax6 has been identified as regulating development of the central nervous system, eyes, nose, pancreas and pituitary gland.
| Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Some Recent Findings
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References
Search Bookshelf Pax
Search Pubmed
Search Pubmed Now: Pax
External Links
- OMIM - PMID: 19736321
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 25) Embryology Developmental Signals - Pax. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Pax
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
