Developmental Signals - Nodal

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Introduction

Nodal together with Lefty are involved in the initial left-right (L-R) patterning of the axis of the embryo. This patterning signal is later used for many cell fate developmental processes.

Left-right (L-R) asymmetry include the position on the left side of the heart and spleen and the development of the curvature of the stomach.


Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular

Some Recent Findings

More recent papers  
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Search term: Nodal

<pubmed limit=5>Nodal</pubmed>

Older papers  
These papers originally appeared in the Some Recent Findings table, but as that list grew in length have now been shuffled down to this collapsible table.

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Nodal Signaling

Nodal represents a family of transmembrane receptors passing only once through the plasma membrane.


Nodal Ligands

Functions

Developmental patterning signal.

Mesoderm Development

StomachDevelopment

Abnormalities

Links:

References

  1. <pubmed>27226324</pubmed>


Reviews

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  • Online Mendelian Inheritance in Man (OMIM) NODAL | LEFTY1


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Cite this page: Hill, M.A. (2024, April 24) Embryology Developmental Signals - Nodal. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Nodal

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G