Developmental Signals - Fox: Difference between revisions
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* '''Tbx1 is regulated by forkhead proteins in the secondary heart field'''.<ref name=PMID16444712><pubmed>16444712</pubmed></ref> "Transcriptional regulation in a tissue-specific and quantitative manner is essential for developmental events, including those involved in cardiovascular morphogenesis. Tbx1 is a T-box-containing transcription factor that is responsible for many of the defects observed in 22q11 deletion syndrome in humans. Tbx1 is expressed in the secondary heart field (SHF) and is essential for cardiac outflow tract (OFT) development....These results suggest that Fox proteins are involved in most, if not all, Tbx1 expression domains and that Tbx1 marks a subset of SHF-derived cells, particularly those that uniquely contribute to the right-sided outflow tract and proximal pulmonary artery." | * '''Tbx1 is regulated by forkhead proteins in the secondary heart field'''.<ref name=PMID16444712><pubmed>16444712</pubmed></ref> "Transcriptional regulation in a tissue-specific and quantitative manner is essential for developmental events, including those involved in cardiovascular morphogenesis. Tbx1 is a T-box-containing transcription factor that is responsible for many of the defects observed in 22q11 deletion syndrome in humans. Tbx1 is expressed in the secondary heart field (SHF) and is essential for cardiac outflow tract (OFT) development....These results suggest that Fox proteins are involved in most, if not all, Tbx1 expression domains and that Tbx1 marks a subset of SHF-derived cells, particularly those that uniquely contribute to the right-sided outflow tract and proximal pulmonary artery." (More? [[Developmental Signals - Tbx|Tbx]] | [[Cardiovascular System Development]] ) | ||
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Revision as of 14:45, 16 June 2015
Embryology - 24 Apr 2024 Expand to Translate |
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Introduction
Draft page.
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Some Recent Findings
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More recent papers |
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More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Fox <pubmed limit=5>Fox</pubmed> |
Transcription Factor
Abnormalities
Associated with defects in each Fox protein or their signaling pathway.
References
- ↑ <pubmed>16444712</pubmed>
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Cite this page: Hill, M.A. (2024, April 24) Embryology Developmental Signals - Fox. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Fox
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G