Developmental Mechanism - Tube Formation: Difference between revisions
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* <ref><pubmed></pubmed></ref> | * '''MIM regulates vertebrate neural tube closure'''<ref><pubmed>21471152</pubmed></ref> "Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although previous studies have uncovered a central role for the non-canonical Wnt signaling pathway in neural tube closure, the underlying mechanism remains poorly resolved. Here, we show that the missing in metastasis (MIM; Mtss1) protein, previously identified as a Hedgehog response gene and actin and membrane remodeling protein, specifically binds to Daam1 and couples non-canonical Wnt signaling to neural tube closure." | ||
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Revision as of 19:48, 14 November 2011
Introduction
Throughout the body are many structures which are described as "tubular", that is they have a cellular wall with a hollow and generally fluid-filled core.
How do you make a "pipe" from cells, are there common mechanisms of this tube formation or a number of different ways of generating hollow structures? In research there does not seem to be a "tube research group", but a number of embryology and cell biology research laboratories are now looking at how cellular tubes form in their particular tissue of interest (heart, blood vessels, neural, gastrointestinal tract, respiratory tract, kidney, genital).
Some Recent Findings
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References
- ↑ <pubmed>21471152</pubmed>
Textbooks
Reviews
<pubmed></pubmed>
Articles
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Cite this page: Hill, M.A. (2024, April 23) Embryology Developmental Mechanism - Tube Formation. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Mechanism_-_Tube_Formation
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G