Difference between revisions of "Developmental Mechanism - Tube Formation"

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Revision as of 20:48, 14 November 2011

Notice - Mark Hill
Currently this page is only a template and will be updated (this notice removed when completed).

Introduction

Throughout the body are many structures which are described as "tubular", that is they have a cellular wall with a hollow and generally fluid-filled core.

How do you make a "pipe" from cells, are there common mechanisms of this tube formation or a number of different ways of generating hollow structures? In research there does not seem to be a "tube research group", but a number of embryology and cell biology research laboratories are now looking at how cellular tubes form in their particular tissue of interest (heart, blood vessels, neural, gastrointestinal tract, respiratory tract, kidney, genital).


Mechanism - "a process, technique, or system for achieving a result".


Mechanism Links: mitosis | cell migration | epithelial invagination | epithelial mesenchymal transition | mesenchymal epithelial transition | epithelial mesenchymal interaction | morphodynamics | tube formation | apoptosis | autophagy | axes formation | time | molecular

Some Recent Findings

  • MIM regulates vertebrate neural tube closure[1] "Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although previous studies have uncovered a central role for the non-canonical Wnt signaling pathway in neural tube closure, the underlying mechanism remains poorly resolved. Here, we show that the missing in metastasis (MIM; Mtss1) protein, previously identified as a Hedgehog response gene and actin and membrane remodeling protein, specifically binds to Daam1 and couples non-canonical Wnt signaling to neural tube closure."

References

  1. <pubmed>21471152</pubmed>


Textbooks

Reviews

<pubmed></pubmed>

Articles

Search PubMed

Search Pubmed: developmental tube formation

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.



Mechanism Links: mitosis | cell migration | epithelial invagination | epithelial mesenchymal transition | mesenchymal epithelial transition | epithelial mesenchymal interaction | morphodynamics | tube formation | apoptosis | autophagy | axes formation | time | molecular


Glossary Links

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Cite this page: Hill, M.A. (2020, February 19) Embryology Developmental Mechanism - Tube Formation. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Mechanism_-_Tube_Formation

What Links Here?
© Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G