Developmental Mechanism - Dorso-Ventral Axis
|Embryology - 11 May 2021 Expand to Translate|
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How do you establish the anatomical axes of the embryo? Another well studied model of axis patterning is the establishment of limb axes, in particular this system historically was studied by grafting and rotating parts of the early developing limb.
Note there is some confusion arising in the terminology when comparing animal developmental axes and those of human anatomical axes.
Left-right axis (L-R) transverse plane
- vertebrates - left side Nodal expression
- sea urchins - right side Nodal expression, inhibit the right mesodermal coelomic pouch (CP) from forming the adult rudiment
- Nodal - induces its own expression and that of Lefty.
- Lefty - a Nodal feedback inhibitor with a longer diffusion range.
|Primitive node cilia (human stage 8)||Embryo left-right asymmetry pathway|
|Axes Formation: left-right axis | dorso-ventral axis | rostro-caudal axis | limb axis | Coronal | Sagittal | Transverse|
Some Recent Findings
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
Search term: Left-Right Axis
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Cite this page: Hill, M.A. (2021, May 11) Embryology Developmental Mechanism - Dorso-Ventral Axis. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Mechanism_-_Dorso-Ventral_Axis
- © Dr Mark Hill 2021, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G