Development Animation - Adrenal Medulla

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Adrenal Medulla Development

This animation shows the dual embryonic origins of the adrenal development.

Adrenal Medulla

  • neural crest origin, migrate adjacent to coelomic cavity, initially uncapsulated and not surrounded by fetal cortex, cells have neuron-like morphology
  • 2 cell types - secrete epinepherine (adrenaline) 80%; secrete norepinepherine (noradrenaline* 20%


Adrenal Cortex

  • mesothelium origin, epithelium lining the body cavity at the site of adrenal development
  • Late Fetal Period - differentiates to form cortical zones
  • Birth - zona glomerulosa, zona fasiculata present
  • Year 3 - zona reticularis present



Medulla

Neural crest cells migrate toward the coelomic cavity wall and form the adrenal medulla. These chromaffin (chromaphil) cells originally named because of their staining (yellow) with chromium salts.

Cortex

Week 4 celomic epithelium (mesothelium) cells proliferate initially forming small buds that separate from the epithelium.

Week 6 these now mesenchymal cells first form the fetal adrenal cortex which will be later replaced by the adult cortex.

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Cite this page: Hill, M.A. (2021, January 26) Embryology Development Animation - Adrenal Medulla. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Development_Animation_-_Adrenal_Medulla

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© Dr Mark Hill 2021, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G