Difference between revisions of "Detailed Cardiac - Sinus Node"
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Functions in survival, proliferation, and function of pacemaker cells throughout development.26193633
Functions in survival, proliferation, and function of pacemaker cells throughout development.
Revision as of 18:20, 18 February 2017
|Embryology - 25 Jul 2021 Expand to Translate|
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|Detailed Cardiac: Systemic Venous Sinus | Pulmonary Vein | Superior Interatrial Fold | Atrioventricular Cushions | Atrioventricular Canal | Interventricular Communication | Subpulmonary Infundibulum | Arterial Roots | Intrapericardial Arterial Trunks | Extrapericardial Arterial Channels | Sinus Node | Atrioventricular Conduction Axis|
Appearance and Remodelling of the Sinus Node
The sinoatrial node (SAN) is the primary pacemaker of the heart that initially develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2.
|Cardiovascular Links: cardiovascular | Heart Tutorial | Lecture - Early Vascular | Lecture - Heart | Movies | 2016 Cardiac Review | heart | coronary circulation | heart valve | heart rate | Circulation | blood | blood vessel | blood vessel histology | heart histology | Lymphatic | ductus venosus | spleen | Stage 22 | cardiovascular abnormalities | OMIM | 2012 ECHO Meeting | Category:Cardiovascular|
Some Recent Findings
|More recent papers|
This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
Search term: Sinus Node Development
<pubmed limit=5>Sinus Node Development</pubmed>
Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4) gene located at 15q24.1, the 1,203 amino acid protein contains 6 putative transmembrane segments, a pore region, and a cyclic nucleotide-binding domain.
- Links: [OMIM HCN4
Short Stature Homeobox 2 (SHOX2) gene located at 3q25.32, the protein acts as a homeobox transcription factor.
- mouse og12 gene - developmental sinus venosus (aorta), female genitalia, diencephalon, mes- and myelencephalon, nasal capsula, palate, eyelid, and limbs
- Links: OMIM SHOX2
ISL Lim Homeobox 1 (ISL1) gene located at 5q11.1 is a member of the LIM/homeodomain family of transcription factors that binds to the enhancer region of the insulin gene. Functions in survival, proliferation, and function of pacemaker cells throughout development.
- Links: OMIM ISL1
<pubmed>26023305</pubmed> <pubmed>24672485</pubmed> <pubmed></pubmed> <pubmed></pubmed>
<pubmed>27291063</pubmed> <pubmed>26682210</pubmed> <pubmed>26611337</pubmed>
Cite this page: Hill, M.A. (2021, July 25) Embryology Detailed Cardiac - Sinus Node. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Detailed_Cardiac_-_Sinus_Node
- © Dr Mark Hill 2021, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G