Category:Wnt
This Embryology category shows pages and media related to the Wnt signalling pathway in development.
A secreted glycoprotein patterning switch with different roles in different tissues and signaling has generally been divided into the canonical and non-canonical pathways. The name was derived from two drosophila phenotypes wingless and int and the gene was first defined as a protooncogene, int1. Humans have 19 identified members, with the major subgroup of Wnts (WNT1, WNT3A, WNT8) signaling through activation of beta-catenin dependent transcription from at least 4 WNT genes encoding secreted glycoproteins. At least one wnt receptor called frizzled (FZD). Wnt7a is secreted protein and binds to extracellular matrix. The mechanism of Wnt distribution (free diffusion, restricted diffusion and active transport) and all its possible cell receptors are still being determined. In the gastrointestinal system, Wnt maintains the pool of undifferentiated intestinal progenitor cells and control maturation and correct positioning of the Paneth cell (a differentiated intestinal cell type).
- Main Page: Wnt
Table - Human Wnt Family | |||||
Approved Symbol |
Approved Name | Previous Symbols |
Synonyms | Chromosome | |
---|---|---|---|---|---|
WNT1 | Wnt family member 1 | INT1 | 12q13.12 | ||
WNT2 | Wnt family member 2 | INT1L1 | IRP | 7q31.2 | |
WNT2B | Wnt family member 2B | WNT13 | XWNT2 | 1p13.2 | |
WNT3 | Wnt family member 3 | INT4 | "MGC131950, MGC138321, MGC138323" | 17q21.31-q21.32 | |
WNT3A | Wnt family member 3A | 1q42.13 | |||
WNT4 | Wnt family member 4 | WNT-4 | 1p36.12 | ||
WNT5A | Wnt family member 5A | hWNT5A | 3p14.3 | ||
WNT5B | Wnt family member 5B | 12p13.33 | |||
WNT6 | Wnt family member 6 | 2q35 | |||
WNT7A | Wnt family member 7A | 3p25.1 | |||
WNT7B | Wnt family member 7B | 22q13.31 | |||
WNT8A | Wnt family member 8A | WNT8D | 5q31.2 | ||
WNT8B | Wnt family member 8B | 10q24.31 | |||
WNT9A | Wnt family member 9A | WNT14 | 1q42.13 | ||
WNT9B | Wnt family member 9B | WNT15 | WNT14B | 17q21.32 | |
WNT10A | Wnt family member 10A | 2q35 | |||
WNT10B | Wnt family member 10B | "WNT-12, SHFM6" | 12q13.12 | ||
WNT11 | Wnt family member 11 | 11q13.5 | |||
WNT16 | Wnt family member 16 | 7q31.31 | |||
Links: Developmental Signals - Wnt | OMIM Wnt1 | HGNC | Bmp Family | Fgf Family | Pax Family | R-spondin Family | Sox Family | Tbx Family | Wnt Family | |||||
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Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Pages in category 'Wnt'
The following 8 pages are in this category, out of 8 total.
Media in category 'Wnt'
The following 18 files are in this category, out of 18 total.
- Canonical Wnt signaling in Wnt5a KO limb buds.jpg 1,280 × 701; 132 KB
- Chicken- limb bud chondrogenesis.jpg 600 × 1,032; 163 KB
- Chicken- neural Wnt expression.jpg 600 × 424; 55 KB
- Chicken- wing cartilage.jpg 1,200 × 1,022; 218 KB
- Chicken-limb sox9 wnt6.jpg 1,173 × 373; 68 KB
- European Wnt Meeting Sep2018.jpg 841 × 1,190; 178 KB
- Female reproductive tract Wnt4.jpg 1,000 × 563; 79 KB
- Gastrulation molecular factors01.jpg 750 × 549; 105 KB
- Hox 3 phase model.jpg 1,030 × 800; 81 KB
- Limb bud geometry and patterning.jpg 583 × 765; 76 KB
- Mouse external genital development.jpg 800 × 701; 75 KB
- Mouse sex determination genes 01.jpg 1,280 × 923; 73 KB
- Mouse Wnt signaling 01.jpg 600 × 450; 156 KB
- Mouse- facial branchiomotor neuron migration.jpg 600 × 841; 104 KB
- Non-canonical Wnt signaling.jpeg 1,280 × 980; 215 KB
- Sea urchin Wnt patterning model.jpg 1,029 × 1,000; 110 KB
- Wnt signal pathway.jpg 1,280 × 422; 125 KB