Carnegie stage 21

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Introduction

Stage21 bf1c.jpg

Facts

Week 8, 53 - 54 days, 22 - 24 mm

Gestational age GA week 10

Summary

  • Ectoderm: sensory placodes, nasal pits moved ventrally, fourth ventricle of brain
  • Mesoderm: heart prominence, ossification continues
  • Head: nose, eye, external acoustic meatus
  • Body: straightening of trunk, heart, liver, umbilical cord
  • Limb: upper limbs longer and bent at elbow, foot plate with digital rays begin to separate, wrist, hand plate with webbed digits

Features

  • scalp vascular plexus, eylid, eye, nose, auricle of external ear, arm, elbow, wrist, knee, notch between digital rays, umbilical cord
  • Identify: straightening of trunk, pigmented eye, eyelid, nose, external acoustic meatus, scalp vascular plexus, webbed digits, liver prominance, thigh, ankle, foot plate, umbilical cord
Links: Week 8 | System Development | Lecture - Limb | Lecture - Head Development | Lecture - Sensory | Science Practical - Head | Science Practical - Sensory | Science Practical - Urogenital | Category:Carnegie Stage 21 | Stage 22


Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline

Bright Field

Stage21 bf11a.jpg

Virtual Embryo Slides

Stage 21 - Left Lateral

Stage21 bf11.jpg

 ‎‎Mobile | Desktop | Original

Stage 21 | Embryo Slides

Kyoto Collection

Stage21 bf1a.jpg

View: This is a dorsolateral view of embryo. Amniotic membrane removed.

Central Nervous System
Human Stage21 neural01.jpg Human Stage21 neural02.jpg
left lateral view medial view
scale bar = 1mm


Image source: The Kyoto Collection images are reproduced with the permission of Prof. Kohei Shiota and Prof. Shigehito Yamada, Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan for educational purposes only and cannot be reproduced electronically or in writing without permission.

Carnegie Collection

Stage21 bf2.jpg Stage21 bf3.jpg Stage21 bf4.jpg Stage21 bf5.jpg Stage21 bf6.jpg Stage21 bf7.jpg Stage21 bf8.jpg Stage21 bf9.jpg Stage21 bf10.jpg

Carnegie stage 21: 7592 Right | 7592 Anterior | 7592 Left | 8553 Right | 8553 Anterior | 8553 Left | 4090 Right | 4090 Anterior | 4090 Left
Carnegie Collection - Stage 21 
Serial No. Size (mm) Grade Fixative Embedding Medium Plane Thinness (µm) Stain Point Score Sex Year Notes
22 E, 20 Ch, 35x30x30 Good Alc. P Transverse 50 Al. coch. 34.5 Female 1895
57 E, 23 Ch., ca. 30 Poor Alc. P Sagittal 50 Al. coch. 36 Male 1896
128 E, 20 Ch., 50x43 Good Formalin P Coronal 50 Al. coch. 33 Female 1898
229 E, 19 Poor Alc. P Sagittal 50 Al. coch. 33 Female 1903
349 E, 24 Good Zenker C Coronal 250 Unstained 36 ? 1905 Double vascular injection
455 E, 24 Ch., 42x34x20 Good Alc. P Transverse 30 (Stain - Haematoxylin Eosin) 36.5 Male 1910
632 E, 24 Ch., 60x50x30 Good Bichlor. acetic P Sagittal 40, 100, 250 Al. coch. 33 Female 1913 Injected
903C E, 23.5 Good Formalin P Transverse 40 Al. coch. 38.5 Female 1914
1008 E, 26,4 Good Formalin P Sagittal 40 Al. coch. 39 ?? 1914
1358F E, 23 Good Formalin P Sagittal 40 Al. coch. 37.5 Female 1916
2937 E,, 24.2 Good Bouin P Transverse 50 (Stain - Haematoxylin Eosin) aur., or. G. 39 Female 1920
3167 E., 24.5 Ch., 60x50x40 Poor Bichlor, acetic, formol P Transverse 20 Al. coch. 32 Male 1920
4090 E, 22.2 Ch.. 66x46x30 Good Formalin P Transverse 40 Al. coch. 30 Female 1922
4160 E,25 Poor Formalin P Sagittal 25 (Stain - Haematoxylin Eosin) 39 Male 1923 Tubal
4960 E.22 Ch,, 47x42x28 Good Formalin P Transverse 15 Al. coch., Mallory 31.5 Female 1925
5??6 E. 215 Good Formalin P Sagittal 20 (Stain - Haematoxylin Eosin) 34 Female 1927
6531 E,22 Poor Glacial acetic, C-P Transverse 10 (Stain - Haematoxylin Eosin) 31.5 Female 1931 Leitz Collection
7254 E,225 Exc Bouin C-P Transverse 20 (Stain - Haematoxylin Eosin) 33.5 Male 1936
7592 E,22-> Exc. Bouin C-P Transverse 20 (Stain - Haematoxylin Eosin) 36 Female 1937
7864 E., 24 Exc, Formalin C-P Frontal 20 (Stain - Haematoxylin Eosin) 32.5 Male 1941
8553 E., 22 Exc Bouin C-P Transverse 12 (Stain - Haematoxylin Eosin) 38 Female 1947
9614 E,,22 5 Exc Bouin P Coronal 10 &15 Azan ? ? 1958 Rubella. Hysterectomy
Abbreviations
  • Size - E. is the greatest length of the embryo and Ch. is the mean diameter of the chorion.
  • Grade - total grade of the specimen and includes both its original quality and the condition of the mounted sections.
  • Embedding medium - paraffin (P) or a combination of celloidin and paraffin (C-P).
  • Fixative - formalin (Formol), alcohol and formalin (Alc, formol), Bouin (Bouin solution)
  • Stain -
  • ? - unknown or not determined.
iBook - Carnegie Embryos  
link=http://itunes.apple.com/au/book/the-carnegie-staged-embryos/id510004473?mt=11 iTunes link
  • iTunes link | iBook Store
  • Description - Imagine the excitement of seeing this incredible early period of human development for the first time. Now consider that much of our initial understanding of human development is based upon study of historic embryo collections. You can now look at these historic images of the first 8 weeks after fertilisation and explore for yourself the changes that occur in human development during this key period. This current book is designed as an atlas of the Carnegie embryo stages with some brief notes and additional information covering the first 8 weeks of development. These images are from from the beginning of last century and are one of the earliest documented series of human embryos collected for basic research and medical education on development. I hope you enjoy learning about the amazing early events that begin to make and shape us. This is the second book in a series of educational releases from UNSW Embryology.
  • Release: First Edition - Mar 12, 2012 ISBN 978-0-7334-3148-7 Print Length 82 Pages, 25.8 MB Language English.
  • PDF Preview version 3.87 MB (Read the associated information, this is an edited educational preview version with many features not functioning).
  • The current website also includes numerous embryo images from this textbook (see Embryonic Development and Carnegie Embryos).

Events

  • Vision - (stage 19 -22) the eyelid folds develop into the eyelids and cover more of the eye as the palpebral fissure takes shape. The upper and the lower eyelids meet at the outer canthus in Stage 19. [1]

References

  1. <pubmed>7364662</pubmed>


Additional Images

Historic Images


Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline




Cite this page: Hill, M.A. (2024, March 29) Embryology Carnegie stage 21. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_21

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G