Carnegie stage 2

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Introduction

Stage2.jpg First cell mitotic divisions of the zygote forming initially 2 blastomeres that continue to divide to form the morula, a "berry", a solid mass of cells.

This early mitosis is a unique embryonic cell cycle (M, S, M phases) compared to adult (M, G1, S, G2, M phase). With virtually no G1 or G2 phases this results in a reduction in cytoplasmic volume of each daughter cell with each cell division.

Summary


See also Events

Stage 2 Links: Week 1 | Morula | Blastocyst | Mitosis | Zona pellucida | Lecture | Medicine Practical | Science Practical | Next Stage 3
  Historic Papers: 1956
Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Stage 2 Day 2 Stage 2 Day 3
Human Embryo (day 2) Human Embryo (day 3)

See also Human oocyte to blastocyst

Carnegie Collection

Stage2 bf01.jpg

Two cell blastomere (1-2 days)


Carnegie Collection - Stage 2 
Serial No. Normality No. of Blastomeres Size of Fixed Specimen (µm) Fixative Embedding Medium Thinness (µm) Stain Year Notes
8190 abnormal 9 160x104 Alc. & Bouin C-P 6 Iron h., or G 1943 Hertig et al. (1954)
8260 in vitro 2 50x75 Bouin C-P 8 (Stain - Haematoxylin Eosin) 1944 Menkin and Rock (1948)
8450 abnormal 8 100x96 Alc. & Bouin C-P 6 (Stain - Haematoxylin Eosin), phlox. 1947 Hertig et al. (1954)
8452 abnormal 12 110x93 Alc. & Bouin C-P 6 (Stain - Haematoxylin Eosin), phlox. 1946 Hertig et al. (1954)
8500.1 in vitro 3 50x86 Bouin C-P 8 (Stain - Haematoxylin Eosin) 1947 Menkin and Rock (1948)
8630 abnormal 5 104x94 Alc. & Bouin C-P 6 (Stain - Haematoxylin Eosin) 1948 Hertig et al. (1954)
8698 normal 2 122x88 Alc. & Bouin C-P 6 (Stain - Haematoxylin Eosin) 1949 Hertig et al. (1954)
8904 normal 12 115 Specimen lost 1951 Hertig et al. (1954)
Abbreviations
  • Embedding medium - paraffin (P) or a combination of celloidin and paraffin (C-P).
  • Fixative - formalin (Formol), alcohol and formalin (Alc, formol), Bouin (Bouin solution)
  • ? - unknown or not determined.

Events

[1]


References

  1. <pubmed></pubmed>

Additional Images

Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline



Cite this page: Hill, M.A. (2024, March 29) Embryology Carnegie stage 2. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_2

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G