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| | | #REDIRECT [[Paper - On the fate of the human embryo in tubal pregnancy (1915)]] |
| Contributions To Embryology
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| Volume I, No. 1
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| Washington, D. C.
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| Published By The Carnegie Institution Ok Washington
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| 1915
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| Carnegie Institution Of Washington Publication No. 221
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| Press Of Gibson Brothers Washington, D. C.
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| On The Fate Of The Human Embryo In Tubal Pregnancy | |
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| By Franklin P. Mall Director of Department of Embryology, Carnegie Institution of Washington
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| ==Contents==
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| Introduction
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| Acknowledgments
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| Cause of tubal pregnancy
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| Tubal pregnancy with normal embryos
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| Tubal pregnancy with pathological embryos
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| Tubal pregnancy with pathological ova
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| Fertility and sterility
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| Implantation in tubal pregnancy
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| Normal implantation in uterus
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| Normal embryos in the tube
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| The trophoblast
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| Normal embryos from 6 to 9 mm. in length
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| Normal embryos over 9 mm. long
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| Conclusions regarding normal implantation
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| Pathological embryos in tubal pregnancy
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| Pathological ova in tubal pregnancy
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| Degeneration of villi and chorion
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| Summary:
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| Cause
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| Normal implantation
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| Tubal pregnancy containing pathological embryos
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| Pathological ova
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| Addendum
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| Description of the individual specimens
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| Bibliography of papers cited
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| Explanation Plates 1, 2, and 3
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| ==Introduction==
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| The following study on tubal pregnancy is to be regarded somewhat as ;i byproduct from our embryological collection. Originally we were of the opinion that the very earliest stages of human development would be found in a recent tubal pregnancy removed by the surgeon. Before 1897 physicians were under the impression that an embryological collection should consist only of normal specimens, and the first tubal pregnancy added to the collection (No. 109) was sent to us by Dr. Gushing because it contained a normal embryo. We soon found that we would not obtain very early specimens by this method from the fact that the diagnosis of tubal pregnancy is made much too late. The smallest normal specimen we have received (No. 808) contained an embryo 6 weeks old. The very small tubes which have been sent invariably contained pathological embryos or small ova without embryos. According to our records 59 per cent of tubal pregnancies fall in the latter class. In 46 carefully selected cases from Dr. Kelly's clinic this percentage is raised to 84.8; if we could collect all cases of tubal pregnancy, the probabilities are that it would be still higher.
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| The normal specimens accumulated slowly among the numbers of our collection below 500. In this group 21 out of 27 specimens, which had been examined by physicians before they were sent to the laboratory, contained normal embryos. Among the specimens that had not been previously examined, only 4 out of 19 were normal. (See table 1.)
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