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* '''Australian Institute of Health and Welfare - Birthweight of babies born to Indigenous mothers'''<ref>AIHW 2014. Birthweight of babies born to Indigenous mothers. Cat. no. IHW 138. Canberra: AIHW. Viewed 5 August 2014 [http://www.aihw.gov.au/publication-detail/?id=60129548202 http://www.aihw.gov.au/publication-detail/?id=60129548202]</ref> "Birthweight of babies born to Indigenous mothers provides an overview of the birthweight of babies born to Indigenous mothers, including recent trends and information on factors associated with birthweight variation. According to data from the National Perinatal Data Collection, 3.9% of all births in 2011 were to Indigenous mothers. Excluding multiple births, 11.2% of liveborn singleton babies born to Indigenous mothers were of low birthweight—2.5 times the rate for non-Indigenous mothers (4.6%). Between 2000 and 2011, there was a statistically significant decline in the low birthweight rate among Indigenous mothers, and the gap in birthweight between babies born to Indigenous and non-Indigenous mothers declined significantly over this period." | * '''Australian Institute of Health and Welfare - Birthweight of babies born to Indigenous mothers'''<ref name=AIHWIndigenousBirthweight2014>AIHW 2014. Birthweight of babies born to Indigenous mothers. Cat. no. IHW 138. Canberra: AIHW. Viewed 5 August 2014 [http://www.aihw.gov.au/publication-detail/?id=60129548202 http://www.aihw.gov.au/publication-detail/?id=60129548202]</ref> "Birthweight of babies born to Indigenous mothers provides an overview of the birthweight of babies born to Indigenous mothers, including recent trends and information on factors associated with birthweight variation. According to data from the National Perinatal Data Collection, 3.9% of all births in 2011 were to Indigenous mothers. Excluding multiple births, 11.2% of liveborn singleton babies born to Indigenous mothers were of low birthweight—2.5 times the rate for non-Indigenous mothers (4.6%). Between 2000 and 2011, there was a statistically significant decline in the low birthweight rate among Indigenous mothers, and the gap in birthweight between babies born to Indigenous and non-Indigenous mothers declined significantly over this period." | ||
* '''Birthweight percentiles by gestational age for births following assisted reproductive technology in Australia and New Zealand, 2002-2010'''<ref name=PMID24908671><pubmed>24908671</pubmed></ref> "The comparison of birthweight percentile charts for ART births and general population births provide evidence that the proportion of SGA births following ART treatment was comparable to the general population for SET fresh cycles and significantly lower for thaw cycles. Both fresh and thaw cycles showed better outcomes for singleton births following SET compared with DET. Policies to promote single embryo transfer should be considered in order to minimize the adverse perinatal outcomes associated with ART treatment." [[Australian Statistics]] | [[Assisted Reproductive Technology]] | * '''Birthweight percentiles by gestational age for births following assisted reproductive technology in Australia and New Zealand, 2002-2010'''<ref name=PMID24908671><pubmed>24908671</pubmed></ref> "The comparison of birthweight percentile charts for ART births and general population births provide evidence that the proportion of SGA births following ART treatment was comparable to the general population for SET fresh cycles and significantly lower for thaw cycles. Both fresh and thaw cycles showed better outcomes for singleton births following SET compared with DET. Policies to promote single embryo transfer should be considered in order to minimize the adverse perinatal outcomes associated with ART treatment." [[Australian Statistics]] | [[Assisted Reproductive Technology]] | ||
* '''Searching for the Definition of Macrosomia through an Outcome-Based Approach'''<ref name=PMID24941024><pubmed>24941024</pubmed>| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100192 PLoS One.]</ref> "Macrosomia has been defined in various ways by obstetricians and researchers. The purpose of the present study was to search for a definition of macrosomia through an outcome-based approach. In a study of 30,831,694 singleton term live births and 38,053 stillbirths in the U.S. Linked Birth-Infant Death Cohort datasets (1995-2004), we compared the occurrence of stillbirth, neonatal death, and 5-min Apgar score less than four in subgroups of birthweight (4000-4099 g, 4100-4199 g, 4200-4299 g, 4300-4399 g, 4400-4499 g, 4500-4999 g vs. reference group 3500-4000 g) and birthweight percentile for gestational age (90th-94th percentile, 95th-96th, and ≥97th percentile, vs. reference group 75th-90th percentile). There was no significant increase in adverse perinatal outcomes until birthweight exceeded the 97th percentile. A birthweight greater than 4500 g in Whites, or 4300 g in Blacks and Hispanics regardless of gestational age is the optimal threshold to define macrosomia. A birthweight greater than the 97th percentile for a given gestational age, irrespective of race is also reasonable to define macrosomia. The former may be more clinically useful and simpler to apply." [[Birth - Macrosomia]] | * '''Searching for the Definition of Macrosomia through an Outcome-Based Approach'''<ref name=PMID24941024><pubmed>24941024</pubmed>| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100192 PLoS One.]</ref> "Macrosomia has been defined in various ways by obstetricians and researchers. The purpose of the present study was to search for a definition of macrosomia through an outcome-based approach. In a study of 30,831,694 singleton term live births and 38,053 stillbirths in the U.S. Linked Birth-Infant Death Cohort datasets (1995-2004), we compared the occurrence of stillbirth, neonatal death, and 5-min Apgar score less than four in subgroups of birthweight (4000-4099 g, 4100-4199 g, 4200-4299 g, 4300-4399 g, 4400-4499 g, 4500-4999 g vs. reference group 3500-4000 g) and birthweight percentile for gestational age (90th-94th percentile, 95th-96th, and ≥97th percentile, vs. reference group 75th-90th percentile). There was no significant increase in adverse perinatal outcomes until birthweight exceeded the 97th percentile. A birthweight greater than 4500 g in Whites, or 4300 g in Blacks and Hispanics regardless of gestational age is the optimal threshold to define macrosomia. A birthweight greater than the 97th percentile for a given gestational age, irrespective of race is also reasonable to define macrosomia. The former may be more clinically useful and simpler to apply." [[Birth - Macrosomia]] | ||
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| colspan="3" |<center>[[Birth_-_Macrosomia|'''High Birth Weight''']]</center> | | colspan="3" |<center>[[Birth_-_Macrosomia|'''High Birth Weight''']]</center> | ||
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==Small for Gestational Age== | ==Small for Gestational Age== | ||
[[File:Gastroschisis birth weight graph.jpg|thumb|300px|Gastroschisis Birth Weight Graph]] | [[File:Gastroschisis birth weight graph.jpg|thumb|300px|Gastroschisis Birth Weight Graph]] | ||
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:'''Links:''' [http://www.statcan.gc.ca/pub/82-221-x/2011002/def/def1-eng.htm Statistics Canada], Vital Statistics, Birth Database. | :'''Links:''' [http://www.statcan.gc.ca/pub/82-221-x/2011002/def/def1-eng.htm Statistics Canada], Vital Statistics, Birth Database. | ||
==Australia - Indigenous== | |||
Data in graphs below from AIHW 2014 Report.<ref name=AIHWIndigenousBirthweight2014>AIHW 2014. Birthweight of babies born to Indigenous mothers. Cat. no. IHW 138. Canberra: AIHW. Viewed 5 August 2014 [http://www.aihw.gov.au/publication-detail/?id=60129548202 http://www.aihw.gov.au/publication-detail/?id=60129548202]</ref> | |||
{| | |||
| [[File:Australian_Indigenous_birthweight_graph_31.jpg|400px]] | |||
| [[File:Australian_Indigenous_birthweight_graph_35.jpg|400px]] | |||
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| Birthweight distribution | |||
| Average Birthweight (2000-2011) | |||
|- | |||
| [[File:Australian Indigenous birthweight graph 41.jpg|400px]] | |||
| [[File:Australian_Indigenous_birthweight_graph_42.jpg|400px]] | |||
|- | |||
| Preterm Birth | |||
| Smoking in Pregnancy | |||
|} | |||
:'''Links:''' [[Australian Statistics]] | [[Birth_-_Preterm|Preterm Birth]] | [[Abnormal_Development_-_Smoking|Smoking]] | |||
==References== | ==References== | ||
Revision as of 14:45, 7 August 2014
Embryology - 18 Apr 2024 Expand to Translate |
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Introduction
There are a variety of prenatal techniques for estimating approximate birth weight that are relevant for preterm, term and prolonged pregnancy. Ultrasound two- and three-dimensional scanning methods are the basis of most current techniques. There are also standard autopsy weight curves that have been developed from second and third trimester fetal and also neonatal autopsy. Low birth weight is accurately defined as a statistical indicator for development. High birthweight definition on the other hand varies in the literature and between countries with a lower cut-off above 4000 gm or 4500 gm.
At birth, infants are generally weighed as soon as possible and may also be monitored during the neonatal period. In Australia, the average birthweight for all babies born in 1991 was 3,350 grams and about the same in 2004 at 3,370 grams.
- Links: Ultrasound | Fetal Origins Hypothesis | Maternal Diabetes | Macrosomia
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Birth Weight <pubmed limit=5>Birth Weight</pubmed> |
Birth Weight Classifications
The primary causes of VLBW are premature birth (born <37 weeks gestation, and often <30 weeks) and intrauterine growth restriction (IUGR), usually due to problems with placenta, maternal health, or to birth defects. Many VLBW babies with IUGR are preterm and thus are both physically small and physiologically immature.
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Birth weight (grams) | less 500 | 500 – 999 | 1,000 – 1,499 | 1,500 – 1,999 | 2,000 – 2,499 | 2,500 – 2,999 | 3,000 – 3,499 | 3,500 – 3,999 | 4,000 – 4,499 | 4,500 – 4,999 | 5,000 or more |
Classification |
Extremely Low Birth Weight
- Less than 500 grams (1 lb 1 oz or less)
- 500 – 999 grams (1 lb 2 oz – 2 lb 3 oz)
Very Low Birth Weight
- 1,000 – 1,499 grams (2 lb 4 oz – 3 lb 4 oz)
Low Birth Weight
- 1,500–1,999 grams (3 lb 5 oz – 4 lb 6 oz)
- 2,000–2,499 grams (4 lb 7 oz – 5 lb 8 oz)
Normal Birth Weight
- 2,500–2,999 grams (5 lb 9 oz – 6 lb 9 oz)
- 3,000–3,499 grams (6 lb 10 oz – 7 lb 11 oz)
- 3,500–3,999 grams (7 lb 12 oz – 8 lb 13 oz)
High Birth Weight
- 4,000–4,499 grams (8 lb 14 oz – 9 lb 14 oz)
- 4,500–4,999 grams (9 lb 15 oz – 11 lb 0 oz)
- 5,000 grams or more (11 lb 1 oz or more)
- see also Birth - Macrosomia
No Background Version
Birth weight (grams) | less 500 | 500 – 999 | 1,000 – 1,499 | 1,500 – 1,999 | 2,000 – 2,499 | 2,500 – 2,999 | 3,000 – 3,499 | 3,500 – 3,999 | 4,000 – 4,499 | 4,500 – 4,999 | 5,000 or more |
Classification |
Small for Gestational Age
(SGA) Term used for infants as having a birth weight more than 2 standard deviations (SD) below the mean or less than the 10th percentile for the gestational age ((GA}}. WHO birthweight definitions are low birthweight as less than 2,500 grams, very low birthweight is less than 1,500 grams and extremely low birthweight: less than 1,000 grams. Growth restriction can be symmetrical (slow development with limited brain growth) or asymmetrical (head circumference and length are preserved and brain growth is relatively spared).
- Symmetric SGA (Weight, head circumference and length all below the 10th percentile) can be due to chromosomal abnormalities, intrauterine infection, severe placental insufficiency and or a constitutionally small infant.
- Asymmetric SGA (Weight below the 10th percentile) can be due to interference with placental function and or interference with maternal health in 3rd trimester.
There are a large number of known relationships between low birth weight and both maternal and fatal abnormalities, a few examples are shown below.
Fetal Gastroschisis
Gastroschisis patients are commonly small for gestational age (SGA, birth weight < 10th centile). Frequency line graphs of the birth weight distribution.[5]
The abnormality is usually situated to the right of the umbilicus and abdominal contents, mainly gastrointestinal, are found outside the anterior body wall. Can occur in isolation and also in association with other gastrointestinal anomalies (intestinal atresia, perforation, necrosis or volvulus). Defects in other organ systems have been reported in up to 35% of children.
Maternal Elevated Testosterone
Maternal elevated testosterone levels is associated with low birth weight in humans. Hyperandrogenism associated with polycystic ovarian syndrome (PCOS) and pre-eclampsia have a higher prevalence of small-for-gestational age newborns. A rat model study suggests that maternal testosterone does not cross the placenta, to directly suppress fetal growth, but affects nutrient delivery to the fetus by down-regulating specific amino acid transporter activity.[6]
High Altitude
Altitude affects growth patterns measured in a a recent Peruvian study of 63,620 healthy infants born at low (150 m) and high (3000-4400 m) altitude were compared. [7] They found that in the third trimester "Mean and median birth weight differences between those born at low and high altitudes reached statistical significance after 35 and 33 weeks, respectively."
Canada
Definition: Live births with a birth weight of 4,500 grams or more, expressed as a percentage of all live births with known birth weight.
High birth weight can result in complications for the infant and mother during birth and may be associated with an increased risk of diabetes.
- Links: Statistics Canada, Vital Statistics, Birth Database.
Australia - Indigenous
Data in graphs below from AIHW 2014 Report.[1]
Birthweight distribution | Average Birthweight (2000-2011) |
Preterm Birth | Smoking in Pregnancy |
- Links: Australian Statistics | Preterm Birth | Smoking
References
- ↑ 1.0 1.1 AIHW 2014. Birthweight of babies born to Indigenous mothers. Cat. no. IHW 138. Canberra: AIHW. Viewed 5 August 2014 http://www.aihw.gov.au/publication-detail/?id=60129548202
- ↑ <pubmed>24908671</pubmed>
- ↑ <pubmed>24941024</pubmed>| PLoS One.
- ↑ <pubmed>23733791</pubmed>
- ↑ <pubmed>22004141</pubmed>| BMC Pediatr.
- ↑ <pubmed>21812961</pubmed>| Reprod Biol Endocrinol.
- ↑ <pubmed>19038011</pubmed>
Articles
<pubmed>19581044</pubmed>
Search Pubmed
Search Pubmed: Low Birth Weight | small for gestational age
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- METoER (Australia) Birth—birth weight, code N
- CDC (USA) Pediatric Nutrition Surveillance System - Birthweight
- WHO Low Birthweight (2004) PDF
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Cite this page: Hill, M.A. (2024, April 18) Embryology Birth Weight. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Birth_Weight
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G