BGDB Practical - Sexual Differentiation: Difference between revisions

From Embryology
Line 10: Line 10:
{|
{|
| [[File:Historic-testis.jpg|120px]]
| [[File:Historic-testis.jpg|120px]]
[[File:Historic-ovary.jpg|200px]]
[[File:Historic-ovary.jpg|200px]]
| Two key systems, neural and reproductive, develop over an extended period from the early embryo to puberty and the emerging adult. The genital system is closely linked developmentally to the urinary system, often called the urogenital system. This practical will therefore also briefly cover early development of the renal system.
 
'''Historic Gonad Images'''
| valign="top" | Two key systems, neural and reproductive, develop over an extended period from the early embryo to puberty and the emerging adult. The genital system is closely linked developmentally to the urinary system, often called the urogenital system. This practical will therefore also briefly cover early development of the renal system.


In understanding embryonic sexual development, think of a cascade of sequence dependent events that transform indifferent gonads, internal and external genitalia into distinct male and female structures. The process begins with gonad differentiation, which itself is tied developmentally back at the initial event of fertilization and the presence of either a Y or X chromosome in the sperm.
In understanding embryonic sexual development, think of a cascade of sequence dependent events that transform indifferent gonads, internal and external genitalia into distinct male and female structures. The process begins with gonad differentiation, which itself is tied developmentally back at the initial event of fertilization and the presence of either a Y or X chromosome in the sperm.

Revision as of 22:30, 29 May 2011

Introduction

BGDsmall.jpg
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio


This practical will introduce the topic of sexual differentiation during development through a series of online resource pages.

Aim: This practical is an introduction to the earliest events in Sexual Differentiation.

Key Concepts: Primordial germ cells, gonad, internal genitalia, external genitalia, ovary, testes, puberty, hormonal changes, gametogenesis, abnormalities.

Background

Historic-testis.jpg

Historic-ovary.jpg

Historic Gonad Images

Two key systems, neural and reproductive, develop over an extended period from the early embryo to puberty and the emerging adult. The genital system is closely linked developmentally to the urinary system, often called the urogenital system. This practical will therefore also briefly cover early development of the renal system.

In understanding embryonic sexual development, think of a cascade of sequence dependent events that transform indifferent gonads, internal and external genitalia into distinct male and female structures. The process begins with gonad differentiation, which itself is tied developmentally back at the initial event of fertilization and the presence of either a Y or X chromosome in the sperm.

The endpoint of development could be considered the post-puberty active reproductive system. Interestingly, recent research is pointing to a link between neural and reproductive systems in how male and female brains may differentially develop under the influence of sex hormones and perhaps even the sex chromosomes.

Genital Timeline

24 days - intermediate mesoderm, pronephros primordium

28 days - mesonephros and mesonephric duct

35 days - uteric bud, metanephros, urogenital ridge

42 days - cloacal divison, gonadal primordium (indifferent)

49 days - paramesonephric duct, gonadal differentiation

56 days - paramesonephric duct fusion (female)

100 days - primary follicles (ovary)

Textbooks

The Developing Human, 8th edn.jpg Moore, K.L. & Persuad, T.V.N. (2008). The Developing Human: clinically oriented embryology (8th ed.). Philadelphia: Saunders.

The following chapter links only work with a UNSW connection and can also be accessed through this UNSW Library connection.

Larsen's human embryology 4th edn.jpg Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R. and Francis-West, P.H. (2009). Larsen’s Human Embryology (4th ed.). New York; Edinburgh: Churchill Livingstone.

The following chapter links only work with a UNSW connection and can also be accessed through this UNSW Library connection.

Logo.png Hill, M.A. (2011) UNSW Embryology (11th ed.). Sydney:UNSW.
Genital Links: genital | Lecture - Medicine | Lecture - Science | Lecture Movie | Medicine - Practical | primordial germ cell | meiosis | endocrine gonad‎ | Genital Movies | genital abnormalities | Assisted Reproductive Technology | puberty | Category:Genital
Female | X | X inactivation | ovary | corpus luteum | oocyte | uterus | vagina | reproductive cycles | menstrual cycle | Category:Female
Male | Y | SRY | testis | spermatozoa | ductus deferens | penis | prostate | Category:Male
Historic Embryology - Genital 
General: 1901 Urinogenital Tract | 1902 The Uro-Genital System | 1904 Ovary and Testis | 1912 Urinogenital Organ Development | 1914 External Genitalia | 1921 Urogenital Development | 1921 External Genital | 1942 Sex Cords | 1953 Germ Cells | Historic Embryology Papers | Historic Disclaimer
Female: 1904 Ovary and Testis | 1904 Hymen | 1912 Urinogenital Organ Development | 1914 External Genitalia | 1914 Female | 1921 External Genital | 1927 Female Foetus 15 cm | 1927 Vagina | 1932 Postnatal Ovary
Male: 1887-88 Testis | 1904 Ovary and Testis | 1904 Leydig Cells | 1906 Testis vascular | 1909 Prostate | 1912 Prostate | 1914 External Genitalia | 1915 Cowper’s and Bartholin’s Glands | 1920 Wolffian tubules | 1935 Prepuce | 1935 Wolffian Duct | 1942 Sex Cords | 1943 Testes Descent | Historic Embryology Papers | Historic Disclaimer



BGDsmall.jpg

BGDB: Lecture - Gastrointestinal System | Practical - Gastrointestinal System | Lecture - Face and Ear | Practical - Face and Ear | Lecture - Endocrine | Lecture - Sexual Differentiation | Practical - Sexual Differentiation | Tutorial


Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link



Cite this page: Hill, M.A. (2024, March 28) Embryology BGDB Practical - Sexual Differentiation. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/BGDB_Practical_-_Sexual_Differentiation

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G