Aschheim-Zondek Test 1928 Movie: Difference between revisions
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| | | width=460px|<html5media height="650" width="450">File:Aschheim-Zondek Test 1928.mp4</html5media> | ||
| valign="top" |This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test. | | valign="top" |[[File:Aschheim-Zondek Test 1928.jpg|thumb]]This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test. | ||
The basis of the original historic Aschheim-Zondek<ref>Aschheim, S., and Zondek, B., Klin. Wschr., 7 8, 1401 (1928).</ref> test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice. These changes could be seen by carrying out histology on the mouse ovary to detect follicle development. | The basis of the original historic Aschheim-Zondek<ref>Aschheim, S., and Zondek, B., Klin. Wschr., 7 8, 1401 (1928).</ref> test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice. These changes could be seen by carrying out histology on the mouse ovary to detect follicle development. | ||
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This early mouse test was later replaced with a similar, but simpler, urine test using either the frog (Xenopus) or rabbit animal models. | This early mouse test was later replaced with a similar, but simpler, urine test using either the frog (Xenopus) or rabbit animal models. | ||
Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG). | Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG). Animation based upon original line drawings.{{#pmid:20318243|PMID20318243}} | ||
Animation based upon original line drawings. | |||
{{Aschheim-Zondek Test 1928}} | {{Aschheim-Zondek Test 1928}} | ||
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===Reference=== | ===Reference=== | ||
<references /> | <references /> | ||
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[[Category:Human]] [[Category:Mouse]] [[Category:Prenatal Diagnosis]] | [[Category:Human]] [[Category:Mouse]] [[Category:Prenatal Diagnosis]] |
Latest revision as of 17:08, 7 September 2018
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<html5media height="650" width="450">File:Aschheim-Zondek Test 1928.mp4</html5media> | This animation shows the basis of the historic 1928 Aschheim-Zondek Pregnancy Test.
The basis of the original historic Aschheim-Zondek[1] test developed in 1928 was to identify the changes in immature female mouse genital system induced by female human urine injected subcutaneously into these immature mice. These changes could be seen by carrying out histology on the mouse ovary to detect follicle development.
This early mouse test was later replaced with a similar, but simpler, urine test using either the frog (Xenopus) or rabbit animal models. Modern home tests use a simple one step urine sample detecting the presence of the hormone human Chorionic Gonadotropin (hCG). Animation based upon original line drawings.[2]
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Cite this page: Hill, M.A. (2024, April 24) Embryology Aschheim-Zondek Test 1928 Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Aschheim-Zondek_Test_1928_Movie
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G