Difference between revisions of "Abnormal Development - Varicella Zoster Virus"

From Embryology
(Created page with "==Introduction== Varicella Zoster Virus or chickenpox maternal infection can be transmitted to the fetus. Fetal varicella syndrome (FVS) is caused by transplacental infectio...")
 
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==Introduction==
 
==Introduction==
  
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* '''during pregnancy''' - transmission can occur, but is usually asymptomatic; some infants develop zoster postnatally and a few have FVS.  
 
* '''during pregnancy''' - transmission can occur, but is usually asymptomatic; some infants develop zoster postnatally and a few have FVS.  
 
* '''around delivery''' - often leads to disseminated neonatal varicella.  
 
* '''around delivery''' - often leads to disseminated neonatal varicella.  
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:{{Viral Links}}
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==Some Recent Findings==
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{|
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<ref><pubmed>19697432</pubmed></ref>
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|}
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==Images==
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==WHO Information==
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==Virus History==
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==References==
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<references/>
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===Textbooks===
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* '''Medical Microbiology'''. 4th edition. Baron S, editor. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. [http://www.ncbi.nlm.nih.gov/books/NBK8200/ Chapter 55 Togaviruses: Rubella Virus] | [http://www.ncbi.nlm.nih.gov/books/NBK7633/ Chapter 54Alphaviruses (Togaviridae) and Flaviviruses (Flaviviridae)] |  [http://www.ncbi.nlm.nih.gov/books/NBK8200/table/A2962/ Table 55-1 Abnormalities Associated with Congenital Rubella Syndrome] |  [http://www.ncbi.nlm.nih.gov/books/NBK8200/figure/A2969/ Figure 55-3 Incidence rates of rubella USA 1966-1993]
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* '''Molecular Biology of the Cell'''. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science; 2002. [http://www.ncbi.nlm.nih.gov/books/NBK26917/#A4628 Viruses Exploit Host Cell Machinery for All Aspects of Their Multiplication]
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* '''Disease Control Priorities in Developing Countries'''. 2nd edition. Jamison DT, Breman JG, Measham AR, et al., editors. Washington (DC): World Bank; 2006.  [http://www.ncbi.nlm.nih.gov/books/NBK11768/ Chapter 20Vaccine-preventable Diseases]
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*''' Antenatal Care: Routine care for the healthy pregnant woman.''' NICE Clinical Guidelines, No. 62. National Collaborating Centre for Women's and Children's Health (UK). London: RCOG Press; 2008 Mar. [http://www.ncbi.nlm.nih.gov/books?term=rubella%20AND%20nicecg62 10.8. Rubella]
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===Reviews===
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<pubmed>16580940</pubmed>
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===Articles===
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<pubmed>11297117</pubmed> | [http://www.mja.com.au/public/issues/174_06_190301/heuchan/heuchan.html eMJA]
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===Search Pubmed===
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'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Varicella+Zoster+Virus Varicella Zoster Virus] | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Congenital+Varicella+Syndrome]  | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=fetal+varicella+syndrome fetal varicella syndrome]
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== External Links ==
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{{External Links}}
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* Department of Health and Ageing [http://www.immunise.health.gov.au Immunise Australia Program Website] |  [http://www.immunise.health.gov.au/internet/immunise/publishing.nsf/Content/Handbook-home  The Australian Immunisation Handbook 9th Edition 2008]
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* '''World Health Organization''' (WHO)
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* [http://www.ICTVonline.org International Committee on Taxonomy of Viruses]
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PMID 11297117 [http://www.mja.com.au/public/issues/174_06_190301/heuchan/heuchan.html eMJA  - Management of varicella-zoster virus exposure and infection in pregnancy and the newborn period])
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[[Category:Abnormal Development]] [[Category:Environmental Abnormalities]] [[Category:Virus]]

Revision as of 15:33, 28 April 2012

Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose.

Introduction

Varicella Zoster Virus or chickenpox maternal infection can be transmitted to the fetus.

Fetal varicella syndrome (FVS) is caused by transplacental infection by the varicella zoster (chickenpox) virus following maternal infection.

Viral Links: viral infection | TORCH | cytomegalovirus | hepatitis | HIV | parvovirus | polio | rubella virus | chickenpox | Lymphocytic Choriomeningitis Virus | Zika virus | human papillomavirus | rotavirus | vaccination | varicella virus | environment
Historic Embryology - Viral 
1941 Rubella Cataracts | 1944 Rubella Defects


Fetal and Neonatal Risks

Risks are dependent on the infection timing.

  • before 20 weeks (GA) - FVS can occur with an incidence of about 1%. The lesions can affect the skin, limbs, central and autonomous nervous systems, eyes, cause calcifications, and growth retardation; mortality is high. Lesions typically follow one or several nerve territories, suggesting that damage results from in utero zoster following primary fetal infection.
  • during pregnancy - transmission can occur, but is usually asymptomatic; some infants develop zoster postnatally and a few have FVS.
  • around delivery - often leads to disseminated neonatal varicella.
Viral Links: viral infection | TORCH | cytomegalovirus | hepatitis | HIV | parvovirus | polio | rubella virus | chickenpox | Lymphocytic Choriomeningitis Virus | Zika virus | human papillomavirus | rotavirus | vaccination | varicella virus | environment
Historic Embryology - Viral 
1941 Rubella Cataracts | 1944 Rubella Defects

Some Recent Findings

[1]

Images

WHO Information

Virus History

References

  1. <pubmed>19697432</pubmed>

Textbooks

Reviews

<pubmed>16580940</pubmed>

Articles

<pubmed>11297117</pubmed> | eMJA


Search Pubmed

Search Pubmed: Varicella Zoster Virus | [1] | fetal varicella syndrome



Environmental Links: Introduction | low folic acid | iodine deficiency | Nutrition | Drugs | Australian Drug Categories | USA Drug Categories | thalidomide | herbal drugs | Illegal Drugs | smoking | Fetal Alcohol Syndrome | TORCH | viral infection | bacterial infection | fungal infection | zoonotic infection | toxoplasmosis | Malaria | maternal diabetes | maternal hypertension | maternal hyperthermia | Maternal Inflammation | Maternal Obesity | hypoxia | biological toxins | chemicals | heavy metals | air pollution | radiation | Prenatal Diagnosis | Neonatal Diagnosis | International Classification of Diseases | Fetal Origins Hypothesis


External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.


Glossary Links

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Cite this page: Hill, M.A. (2019, December 15) Embryology Abnormal Development - Varicella Zoster Virus. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Varicella_Zoster_Virus

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G