Abnormal Development - Maternal Inflammation: Difference between revisions
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==Introduction== | ==Introduction== | ||
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==Some Recent Findings== | ==Some Recent Findings== | ||
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* '''Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse.''' | * '''Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse.'''{{#pmid:21935422|PMID21935422}} "Cellular uptake of proteins from the cerebrospinal fluid was observed in brains from lipopolysaccharide-treated animals in radial progenitor cells. However, the foetal blood-brain barrier to plasma proteins remained intact. Together, these results indicate that maternal inflammation can disrupt the ventricular surface and lead to decreased cellular proliferation. Changes in cell density in Layers IV and V at post-natal Day 8 show that these initial changes have prolonged effects on cortical organization. The possible shift in the fate of progeny and the resulting alterations in the relative cell numbers in the cerebral cortex following a maternal inflammatory response shown here will require further investigation to determine the long-term consequences of inflammation on the development of neuronal circuitry and behaviour." | ||
* '''Systemic maternal inflammation and neonatal hyperoxia induces remodeling and left ventricular dysfunction in mice'''{{#pmid:21964917|PMID21964917}} "These results demonstrate that systemic maternal inflammation combined with neonatal hyperoxia exposure induces alterations in cardiac structure and function leading to cardiac failure in adulthood and supports the importance of the intrauterine and neonatal milieu on adult health." | |||
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Search term: [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Maternal%20Inflammation ''Maternal Inflammation''] | |||
<pubmed limit=5>Maternal Inflammation</pubmed> | |||
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==References== | ==References== | ||
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===Articles=== | ===Articles=== | ||
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===Search Pubmed=== | ===Search Pubmed=== | ||
'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Maternal+Inflammation Maternal Inflammation] | '''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Maternal+Inflammation Maternal Inflammation] | ||
== External Links == | == External Links == | ||
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[[Category:Abnormal Development]] [[Category:Environmental Abnormalities]] | [[Category:Abnormal Development]] [[Category:Environmental Abnormalities]] |
Latest revision as of 22:12, 19 March 2018
Embryology - 23 Apr 2024 Expand to Translate |
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Introduction
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Maternal Inflammation <pubmed limit=5>Maternal Inflammation</pubmed> |
References
- ↑ Velten M, Hutchinson KR, Gorr MW, Wold LE, Lucchesi PA & Rogers LK. (2011). Systemic maternal inflammation and neonatal hyperoxia induces remodeling and left ventricular dysfunction in mice. PLoS ONE , 6, e24544. PMID: 21935422 DOI.
- ↑ Stolp HB, Turnquist C, Dziegielewska KM, Saunders NR, Anthony DC & Molnár Z. (2011). Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse. Brain , 134, 3236-48. PMID: 21964917 DOI.
Reviews
Articles
Unal ER, Cierny JT, Roedner C, Newman R & Goetzl L. (2011). Maternal inflammation in spontaneous term labor. Am. J. Obstet. Gynecol. , 204, 223.e1-5. PMID: 21376162 DOI.
Williams CL, Teeling JL, Perry VH & Fleming TP. (2011). Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring. BMC Biol. , 9, 49. PMID: 21771319 DOI.
Hava G, Vered L, Yael M, Mordechai H & Mahoud H. (2006). Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy. Dev Psychobiol , 48, 162-8. PMID: 16489598 DOI.
Search Pubmed
Search Pubmed: Maternal Inflammation
External Links
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Cite this page: Hill, M.A. (2024, April 23) Embryology Abnormal Development - Maternal Inflammation. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Maternal_Inflammation
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G