ANAT2341 Lab 5

1. QUIZ

2. Guest Lecturer - Dr. Vashe Chandrakanthan

Dr. Vashe Chandrakanthan

Cardiac and Vascular Development and Haematopoiesis

Dr Vashe Chandrakanthan earned his PhD in Medicine from University of Sydney and completed his postdoctoral studies at the Victor Chang Cardiac Research Institute in Sydney.

Currently he is a Research Fellow at the Lowy Cancer Research Centre at the UNSW Australia. He is a member of the adult cancer program where he heads the mesenchymal stem cell biology team. He joined the stem cell program to help setting up a regenerative medicine program at the UNSW Australia.

Dr Chandrakanthan’s primary research interest lies in the field of developmental and molecular biology of stem cells. During his tenure at the Lowy Cancer Research Centre, in addition to setting up the regenerative medicine program, he has lineage traced mesenchymal stem cells and evaluated their contribution to various tissues in the mouse embryo with a particular focus on their role in haematopoiesis.

References

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15 (link is external)

Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55 (link is external)

Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15 (link is external)