Difference between revisions of "ANAT2341 Lab 2"

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PRACTICAL CLASS PROGRAM:
== 1. QUIZ ==
 
  
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* Weekly Quiz + revision (15 minutes)
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* Practical class activities: (45 minutes)
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* Guest Lecture by [https://wch.med.unsw.edu.au/people/associate-professor-robert-gilchrist Professor Robert Gilchrist] (45 minutes)
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* Practical Class Revision (15 minutes)
  
==2. Guest Lecturer - A/Prof Robert Gilchrist ==
 
[[File:Oocyte BMP15 and GDF9 effects.jpg|thumb|Oocyte BMP15 and GDF9 effects PMID 25058588]]
 
{|
 
  
| [[File:Rob Gilchrist.jpg|left|150px|alt=Associate Professor Robert Gilchrist|link=https://research.unsw.edu.au/people/associate-professor-robert-bruce-gilchrist]]
 
  
A/Prof Robert Gilchrist
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PRACTICAL CLASS ACTIVITIES:
| '''The Reproductive Technology Revolution'''
 
<br><br>
 
Dr Gilchristis head of the Oocyte Biology Research Unit (UNSW) his primary research interests are in the regulation of mammalian oocyte development and maturation, and the development of novel oocyte maturation techniques for infertility treatment.
 
  
[[Media:2017 Anatomy IVF and embryology lab.pdf|Lecture Slides]]
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# Virtual human embryo dissections and histology
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# Embryo models and specimens of human developmental abnormalities (optional)
  
<br><br>
 
  
Links: [https://research.unsw.edu.au/people/associate-professor-robert-bruce-gilchrist UNSW Research Gateway] |  [http://www.ncbi.nlm.nih.gov/pubmed/?term=Gilchrist+R%5BAuthor%5D PubMed]
 
|-
 
|}
 
  
===Recent Articles===
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LEARNING OBJECTIVES:
{{#pmid:27422885|PMID27422885}}
 
  
:"The cyclic nucleotides, cAMP and cGMP, are the key molecules controlling mammalian oocyte meiosis. Their roles in oocyte biology have been at the forefront of oocyte research for decades and many of the long standing controversies in relation to the regulation of oocyte meiotic maturation are now resolved. It is now clear that the follicle prevents meiotic resumption through the actions of natriuretic peptides and cGMP inhibiting the hydrolysis of intra-oocyte cAMP and that the preovulatory gonadotrophin surge reverses these processes. The gonadotrophin surge also leads to a transient spike in cAMP in the somatic compartment of the follicle; research over the past 2 decades has conclusively demonstrated that this surge in cAMP is important for the subsequent developmental capacity of the oocyte. This is important, as oocyte in vitro maturation (IVM) systems practiced clinically do not recapitulate this cAMP surge in vitro, possibly accounting for the lower efficiency of IVM compared to clinical IVF. This review focuses in particular on this latter aspect - the role of cAMP/cGMP in the regulation of oocyte quality. We conclude that clinical practice of IVM should reflect this new understanding of the role of cyclic nucleotides, thereby creating a new generation of ART and fertility treatment options."
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* Understanding of reproductive technologies
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* Understanding of events during early ectoderm and mesoderm development
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* Understanding of the process of neurulation and neural crest formation
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* Understanding of the adult components derived from ectoderm and mesoderm
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* Understanding the process of body cavity formation
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* Brief understanding of early heart formation
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* Brief understanding of abnormalities associated with early ectoderm and mesoderm development
  
{{#pmid:27248769|PMID27248769}}
 
  
{{#pmid:27160446|PMID27160446}}
 
  
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PRACTICAL CLASS NOTES:
  
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The Practical class notes are available on [https://moodle.telt.unsw.edu.au/mod/url/view.php?id=2398854 Moodle].
 
 
{{2018ANAT2341}}
 

Latest revision as of 11:41, 26 September 2019

PRACTICAL CLASS PROGRAM:

  • Weekly Quiz + revision (15 minutes)
  • Practical class activities: (45 minutes)
  • Guest Lecture by Professor Robert Gilchrist (45 minutes)
  • Practical Class Revision (15 minutes)


PRACTICAL CLASS ACTIVITIES:

  1. Virtual human embryo dissections and histology
  2. Embryo models and specimens of human developmental abnormalities (optional)


LEARNING OBJECTIVES:

  • Understanding of reproductive technologies
  • Understanding of events during early ectoderm and mesoderm development
  • Understanding of the process of neurulation and neural crest formation
  • Understanding of the adult components derived from ectoderm and mesoderm
  • Understanding the process of body cavity formation
  • Brief understanding of early heart formation
  • Brief understanding of abnormalities associated with early ectoderm and mesoderm development


PRACTICAL CLASS NOTES:

The Practical class notes are available on Moodle.